Concepedia

Kenneth L. Rock

KL

152

Publications

30.2K

Citations

75

H-Index

1976

Active since

Affiliations

University of Massachusetts Chan Medical School(Current)

Harvard University

Dana-Farber Cancer Institute

City Of Hope National Medical Center

Michigan State University

Kenneth L. Rock is an author at University of Massachusetts Chan Medical School specializing in medicine, immunology, and cell biology.

Top concepts

MedicineImmunologyCell BiologyAutoimmunityImmunotherapyAutoimmune DiseaseCell SignalingAllergyT Cell ImmunityNatural Sciences

Publications per year

1976–2022

152

Publications

152

NLRP3 inflammasomes are required for atherogenesis and activated by cholesterol crystals

Peter Duewell, Hajime Kono, Katey J. Rayner et al. · Nature · 2010 · 3.8K citations · Full text

Inflammation, Signal Transduction, Oxysterol +12

Silica crystals and aluminum salts activate the NALP3 inflammasome through phagosomal destabilization

Veit Hornung, Franz Bauernfeind, Annett Halle et al. · Nature Immunology · 2008 · 3K citations · Full text

Nalp3 Inflammasome, Aluminum Salts, Membrane Biology +5

Inhibitors of the proteasome block the degradation of most cell proteins and the generation of peptides presented on MHC class I molecules

Kenneth L. Rock, Colette F. Gramm, Lisa Rothstein et al. · Cell · 1994 · 2.5K citations

Proteasome Block, Biochemistry, Mhc Class +13

Molecular identification of a danger signal that alerts the immune system to dying cells

Yan Shi, James Evans, Kenneth L. Rock · Nature · 2003 · 1.6K citations

Inflammation, Immune Evasion, Systems Biology +14

A Phagosome-to-Cytosol Pathway for Exogenous Antigens Presented on MHC Class I Molecules

Magdalena Kovacsovics-Bankowski, Kenneth L. Rock · Science · 1995 · 871 citations

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