Concepedia

Inhibitors of the proteasome block the degradation of most cell proteins and the generation of peptides presented on MHC class I molecules

Kenneth L. Rock, Colette F. Gramm, Lisa Rothstein, Karen Clark, Ross L. Stein, Lawrence R. Dick, Daniel Hwang, Alfred L. Goldberg

Cell · 1994 · 2.5K citations · 35 references

DOI

Concepts

References

35

Selective rejection of H–2-deficient lymphoma variants suggests alternative immune defence strategy

Klas Kärre, Hans Ljunggren, Gerald E. Piontek et al. · Nature · 1986 · 2.1K citations

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Introduction of soluble protein into the class I pathway of antigen processing and presentation

Mark W. Moore, Francis R. Carbone, Michael J. Bevan · Cell · 1988 · 1.1K citations

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Intracellular Protein Degradation in Mammalian and Bacterial Cells: Part 2

AL Goldberg, A. John · Annual Review of Biochemistry · 1976 · 1.1K citations

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Monoclonal antibodies to mouse MHC antigens. III. Hybridoma antibodies reacting to antigens of the H-2b haplotype reveal genetic control of isotype expression.

Keiko Ozato, David H. Sachs · The Journal of Immunology · 1981 · 572 citations · Full text

, , +14

γ-Interferon and expression of MHC genes regulate peptide hydrolysis by proteasomes

Maria Gaczyńska, Kenneth L. Rock, Alfred L. Goldberg · Nature · 1993 · 572 citations

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