Inhibitors of the proteasome block the degradation of most cell proteins and the generation of peptides presented on MHC class I molecules

Kenneth L. Rock, Colette F. Gramm, Lisa Rothstein, +5

Cell

Proteasome BlockBiochemistryMhc ClassProtein FoldingMedicine +11

Presentation of Exogenous Antigen with Class I Major Histocompatibility Complex Molecules

Kenneth L. Rock, S Gamble, Lisa Rothstein

Science

HistocompatibilitySoluble AntigensHla ImmunogeneticsImmunologyPathology +20

Characterization of antigen-presenting cells that present exogenous antigens in association with class I MHC molecules

Kenneth L. Rock, Lisa Rothstein, S Gamble, +1

The Journal of Immunology

Dissociation of β2-microglobulin leads to the accumulation of a substantial pool of inactive class I MHC heavy chains on the cell surface

Kenneth L. Rock, S Gamble, Lisa Rothstein, +2

Cell

Protein FoldingNatural SciencesCell InteractionImmunologyGlycobiology +11

Reassociation with beta 2-microglobulin is necessary for Kb class I major histocompatibility complex binding of exogenous peptides.

Kenneth L. Rock, Lisa Rothstein, S Gamble, +1

Proceedings of the National Academy of Sciences

HistocompatibilityHla ImmunogeneticsImmunologyMolecular BiologyImmunologic Mechanism +16

Generation of class I MHC-restricted T-T hybridomas.

Kenneth L. Rock, Lisa Rothstein, S Gamble

The Journal of Immunology

HistocompatibilityImmunogeneticsAutoimmune DiseaseAllergyT-t Hybridomas +12

Elimination of clonogenic Burkitt's lymphoma cells from human bone marrow using 4-hydroperoxycyclophosphamide in combination with monoclonal antibodies and complement

Paolo de Fabritiis, Marco Bregni, Jeffrey M. Lipton, +6

Blood

Radiosensitivity of Human Bone Marrow Granulocyte-Macrophage Progenitor Cells and Stromal Colony-Forming Cells: Effect of Dose Rate

Thomas J. FitzGerald, Michael G. McKenna, Lisa Rothstein, +3

Radiation Research

Regenerative MedicineBone Marrow FailureStromal Colony-forming CellsRadiation BiologyMedicine +13

Reassociation with beta 2-microglobulin is necessary for Db class I major histocompatibility complex binding of an exogenous influenza peptide.

Kenneth L. Rock, S Gamble, Lisa Rothstein, +1

Proceedings of the National Academy of Sciences

Exogenous Influenza PeptideImmunologyImmunodominanceImmunologic MechanismAntigen Processing +14

Effect of x-irradiation dose rate on the clonagenic survival of human and experimental animal hematopoietic tumor cell lines: Evidence for heterogeneity

Thomas J. FitzGerald, Michael G. McKenna, Kenneth R. Kase, +3

International Journal of Radiation Oncology*Biology*Physics

Clonagenic SurvivalRadiobiologyRadiation TherapyMedicineRadiation Effect +9