Lawrence R. Dick - Concepedia

Author

Lawrence R. Dick

Millennium Engineering and Integration (United States)ORCID

Also Known As

L R Dick, L. R. DICK, L. R. Dick, Larry Dick, Lawrence Dick, Lawrence R Dick, Lawrence R. Dick, Lawrence Robert Dick, Lawrence R. Dick

Publications

13.2K

Citations

H-Index

Concepts

All Affiliations

Millennium Engineering and Integration (United States)Takeda (United States)The University of Texas Southwestern Medical Center The University of Melbourne Allscripts (United States)

About

Lawrence R. Dick is an author at Millennium Engineering and Integration (United States) specializing in natural sciences, medicine, and biochemistry.

Top Concepts

#	Concept	H-Index	Publications	Citations
1	Natural Sciences	20	22	5.8K
2	Medicine	19	20	7.2K
3	Biochemistry	17	19	5.1K
4	Cell Biology	4	4	723
5	Biomolecular Engineering	2	2	454

Lawrence R. Dick

Publications

10.2K

Citations

H-Index

Page 1

	Year	Citations
Inhibitors of the proteasome block the degradation of most cell proteins and the generation of peptides presented on MHC class I molecules Kenneth L. Rock, Colette F. Gramm, Lisa Rothstein, Cell Proteasome BlockBiochemistryMhc ClassProtein FoldingMedicine	1994	2.5K
An inhibitor of NEDD8-activating enzyme as a new approach to treat cancer Teresa A. Soucy, Peter G. Smith, Michael A. Milhollen, Nature Novel TherapyMedicineNew ApproachAnti-cancer AgentTumor Suppressor	2009	2K
Potent and selective inhibitors of the proteasome: Dipeptidyl boronic acids Julian Adams, Mark L. Behnke, Shaowu Chen, Bioorganic & Medicinal Chemistry Letters Medicinal ChemistryBiochemistryNatural SciencesMedicineDipeptidyl Boronic Acids	1998	680
Substrate-Assisted Inhibition of Ubiquitin-like Protein-Activating Enzymes: The NEDD8 E1 Inhibitor MLN4924 Forms a NEDD8-AMP Mimetic In Situ James E. Brownell, Michael D. Sintchak, James M. Gavin, Molecular Cell Protein ChemistryNedd8-amp MimeticProtein FunctionBiochemistryProtein Folding	2010	457
A small-molecule inhibitor of the ubiquitin activating enzyme for cancer treatment Marc L. Hyer, Michael A. Milhollen, Jeff Ciavarri, Nature Medicine MedicineAnti-cancer AgentSmall-molecule InhibitorDrug DevelopmentBiomolecular Engineering	2018	414
Mechanistic Studies on the Inactivation of the Proteasome by Lactacystin Lawrence R. Dick, Amy A. Cruikshank, Louis Grenier, Journal of Biological Chemistry Active Lactacystin AnalogBiosynthesisMechanistic StudiesCellular EnzymologyBiochemistry	1996	369
MLN4924, a NEDD8-activating enzyme inhibitor, is active in diffuse large B-cell lymphoma models: rationale for treatment of NF-κB–dependent lymphoma Michael A. Milhollen, Tary Traore, Jennifer Adams-Duffy, Blood	2010	320
Artemisinin kills malaria parasites by damaging proteins and inhibiting the proteasome Jessica L. Bridgford, Stanley C. Xie, Simon A. Cobbold, Nature Communications	2018	294
Mechanistic Studies on the Inactivation of the Proteasome by Lactacystin in Cultured Cells Lawrence R. Dick, Amy A. Cruikshank, Antonia T. Destree, Journal of Biological Chemistry	1997	227
Probing the roles of SUMOylation in cancer cell biology by using a selective SAE inhibitor Xingyue He, Jessica Riceberg, Teresa A. Soucy, Nature Chemical Biology Selective Sae InhibitorOncogenic AgentMedicineNatural SciencesMolecular Biology	2017	223

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