Michael A. Milhollen

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Publications

Citations

5.5K

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Active since

1996

Affiliations

Millennium Engineering and Integration (United States)(Current)

Takeda (United States)

Whitehead Institute for Biomedical Research

Dana-Farber Cancer Institute

Howard Hughes Medical Institute

Michael A. Milhollen is an author at Millennium Engineering and Integration (United States) specializing in oncology, molecular oncology, and life sciences.

ORCID

Publications per year

1996–2021

Publications

An inhibitor of NEDD8-activating enzyme as a new approach to treat cancer

Teresa A. Soucy, Peter G. Smith, Michael A. Milhollen et al. · Nature · 2009 · 2K citations

Medicine, Medicinal Chemistry, Oncology +8

Substrate-Assisted Inhibition of Ubiquitin-like Protein-Activating Enzymes: The NEDD8 E1 Inhibitor MLN4924 Forms a NEDD8-AMP Mimetic In Situ

James E. Brownell, Michael D. Sintchak, James M. Gavin et al. · Molecular Cell · 2010 · 461 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +16

A small-molecule inhibitor of the ubiquitin activating enzyme for cancer treatment

Marc L. Hyer, Michael A. Milhollen, Jeff Ciavarri et al. · Nature Medicine · 2018 · 456 citations

Pharmacy, Medicinal Chemistry, Oncology +14

Identification of <scp>d</scp> -Peptide Ligands Through Mirror-Image Phage Display

Ton N. Schumacher, Lorenz M. Mayr, Daniel L. Minor et al. · Science · 1996 · 376 citations

Life Sciences, Biochemistry, Molecular Biology +17

MLN4924, a NEDD8-activating enzyme inhibitor, is active in diffuse large B-cell lymphoma models: rationale for treatment of NF-κB–dependent lymphoma

Michael A. Milhollen, Tary Traore, Jennifer Adams-Duffy et al. · Blood · 2010 · 323 citations · Full text

Medicine, Molecular Biology, Oncology +11

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