Concepedia

Monoclonal antibodies against the 4-1BB T-cell activation molecule eradicate established tumors

Ignacio Melero, Walter W. Shuford, S A Newby, Alejandro Aruffo, Jeffrey A. Ledbetter, Karl Erik Hellström, Robert S. Mittler, Lieping Chen

Nature Medicine · 1997 · 891 citations · 21 references

DOI

Concepts

References

21

Enhancement of Antitumor Immunity by CTLA-4 Blockade

Dana R. Leach, Matthew F. Krummel, James P. Allison · Science · 1996 · 3.9K citations

, , +17

CTLA-4 can function as a negative regulator of T cell activation

Theresa L. Walunas, Deborah J. Lenschow, Christina Y. Bakker et al. · Immunity · 1994 · 2.2K citations

, , +14

Tumor Rejection After Direct Costimulation of CD8 <sup>+</sup> T Cells by B7-Transfected Melanoma Cells

Sarah E. Townsend, James P. Allison · Science · 1993 · 1.1K citations

, , +17

Costimulation of antitumor immunity by the B7 counterreceptor for the T lymphocyte molecules CD28 and CTLA-4

Lieping Chen, Stephanie Ashe, William Brady et al. · Cell · 1992 · 1.1K citations

, , +16

Fundamental Immunology

Philip C. Anderson · JAMA · 1994 · 904 citations

, , +6