Concepedia

CTLA-4 can function as a negative regulator of T cell activation

Theresa L. Walunas, Deborah J. Lenschow, Christina Y. Bakker, Peter S. Linsley, Gordon J. Freeman, Jonathan M. Green, Craig B. Thompson, Jeffrey A. Bluestone

Immunity · 1994 · 2.2K citations · 33 references

DOI

Concepts

References

33

CTLA-4 is a second receptor for the B cell activation antigen B7.

Peter S. Linsley, William Brady, M Urnes et al. · The Journal of Experimental Medicine · 1991 · 1.7K citations · Full text

, , +17

Identification of a monoclonal antibody specific for a murine T3 polypeptide.

Oberdan Léo, M Foo, David H. Sachs et al. · Proceedings of the National Academy of Sciences · 1987 · 1.6K citations · Full text

, , +16

CD28-mediated signalling co-stimulates murine T cells and prevents induction of anergy in T-cell clones

Fiona Harding, James G. McArthur, Jane A. Gross et al. · Nature · 1992 · 1.6K citations

, , +14

A new member of the immunoglobulin superfamily—CTLA-4

Jean‐François Brunet, François Denizot, Marie‐Françoise Luciani et al. · Nature · 1987 · 1.3K citations

, , +11

Characterization of a monoclonal antibody directed against mouse macrophage and lymphocyte Fc receptors.

Jay C. Unkeless · The Journal of Experimental Medicine · 1979 · 1.3K citations · Full text

, , +16