William Brady

CTLA-4 is a second receptor for the B cell activation antigen B7.

Peter S. Linsley, William Brady, M Urnes et al. · The Journal of Experimental Medicine · 1991 · 1.7K citations · Full text

Functional Properties, Functional Interactions, Adaptive Immune System +14

Binding of the B cell activation antigen B7 to CD28 costimulates T cell proliferation and interleukin 2 mRNA accumulation.

P S Linsley, William Brady, Laura S. Grosmaire et al. · The Journal of Experimental Medicine · 1991 · 1.1K citations · Full text

Mrna Accumulation, Adaptive Immune System, Cellular Immunology +16

Long-Term Survival of Xenogeneic Pancreatic Islet Grafts Induced by CTLA4lg

Deborah J. Lenschow, Yijun Zeng, J. Richard Thistlethwaite et al. · Science · 1992 · 1.1K citations

Costimulation of antitumor immunity by the B7 counterreceptor for the T lymphocyte molecules CD28 and CTLA-4

Lieping Chen, Stephanie Ashe, William Brady et al. · Cell · 1992 · 1.1K citations

Immunological Memory, Cancer Immunosurveillance, Autoimmune Disease +10

Human B7-1 (CD80) and B7-2 (CD86) bind with similar avidities but distinct kinetics to CD28 and CTLA-4 receptors

P S Linsley, JoAnne L. Greene, William Brady et al. · Immunity · 1994 · 961 citations

Human B7-1, Signal Transduction, Autoimmune Disease +13