P S Linsley

Binding of the B cell activation antigen B7 to CD28 costimulates T cell proliferation and interleukin 2 mRNA accumulation.

P S Linsley, William Brady, Laura S. Grosmaire et al. · The Journal of Experimental Medicine · 1991 · 1.1K citations · Full text

Mrna Accumulation, Adaptive Immune System, Cellular Immunology +16

Human B7-1 (CD80) and B7-2 (CD86) bind with similar avidities but distinct kinetics to CD28 and CTLA-4 receptors

P S Linsley, JoAnne L. Greene, William Brady et al. · Immunity · 1994 · 961 citations

Human B7-1, Signal Transduction, Autoimmune Disease +13

Coexpression and functional cooperation of CTLA-4 and CD28 on activated T lymphocytes.

P S Linsley, JoAnne L. Greene, Peng Tan et al. · The Journal of Experimental Medicine · 1992 · 582 citations · Full text

B7 Molecule, Adaptive Immune System, T-regulatory Cell +18

Induction of alloantigen-specific hyporesponsiveness in human T lymphocytes by blocking interaction of CD28 with its natural ligand B7/BB1.

Patrick Tan, Claudio Anasetti, John A. Hansen et al. · The Journal of Experimental Medicine · 1993 · 476 citations · Full text

T Cell Hyporesponsiveness, Adaptive Immune System, T-regulatory Cell +17

Immunoglobulin signal transduction guides the specificity of B cell-T cell interactions and is blocked in tolerant self-reactive B cells.

Michael P. Cooke, Andrew W. Heath, Kevan M. Shokat et al. · The Journal of Experimental Medicine · 1994 · 332 citations · Full text

Helper T, Adaptive Immune System, Cellular Immunology +22