Deborah J. Lenschow

CTLA-4 can function as a negative regulator of T cell activation

Theresa L. Walunas, Deborah J. Lenschow, Christina Y. Bakker et al. · Immunity · 1994 · 2.2K citations

T Cell Activation, Signal Transduction, Autoimmune Disease +11

B7/CD28 Costimulation Is Essential for the Homeostasis of the CD4+CD25+ Immunoregulatory T Cells that Control Autoimmune Diabetes

Deborah J. Lenschow, Lesley Rhee, Neda Ashourian et al. · Immunity · 2000 · 2K citations · Full text

Control Autoimmune Diabetes, Autoimmune Disease, B7/cd28 Costimulation +9

Long-Term Survival of Xenogeneic Pancreatic Islet Grafts Induced by CTLA4lg

Deborah J. Lenschow, Yijun Zeng, J. Richard Thistlethwaite et al. · Science · 1992 · 1.1K citations

Identification of a candidate therapeutic autophagy-inducing peptide

Sanae Shoji-Kawata, Rhea Sumpter, Matthew Leveno et al. · Nature · 2013 · 750 citations · Full text

Cell Autophagy, Mitophagy, Autoimmune Disease +9

Differential effects of anti-B7-1 and anti-B7-2 monoclonal antibody treatment on the development of diabetes in the nonobese diabetic mouse.

Deborah J. Lenschow, Shu‐Chuan Ho, Husain Sattar et al. · The Journal of Experimental Medicine · 1995 · 587 citations · Full text

Immunology, Pathology, Immunotherapy +17