Regulating Intracellular Antiviral Defense and Permissiveness to Hepatitis C Virus RNA Replication through a Cellular RNA Helicase, RIG-I

Rhea Sumpter, Yueh–Ming Loo, Eileen Foy, +5

Journal of Virology

Viral ReplicationCellular Rna HelicaseImmunologyMolecular BiologyHcv Rna Replication +16

Prohibitin 2 Is an Inner Mitochondrial Membrane Mitophagy Receptor

Yongjie Wei, Wei‐Chung Chiang, Rhea Sumpter, +2

Cell

MitophagyMitochondrial FunctionMitochondrial DynamicProhibitin 2Autophagy +2

Regulation of Interferon Regulatory Factor-3 by the Hepatitis C Virus Serine Protease

Eileen Foy, Kui Li, Chunfu Wang, +4

Science

Interferon Regulatory Factor-3Viral ReplicationMolecular VirologyViral HepatitisUnrelated Virus +13

Identification of a candidate therapeutic autophagy-inducing peptide

Sanae Shoji-Kawata, Rhea Sumpter, Matthew Leveno, +21

Nature

Cell AutophagyMitophagyAutoimmune DiseaseAutoantibody ProductionMedicine +7

Autosis is a Na ⁺ ,K ⁺ -ATPase–regulated form of cell death triggered by autophagy-inducing peptides, starvation, and hypoxia–ischemia

Yang Liu, Sanae Shoji-Kawata, Rhea Sumpter, +10

Proceedings of the National Academy of Sciences

Control of antiviral defenses through hepatitis C virus disruption of retinoic acid-inducible gene-I signaling

Eileen Foy, Kui Li, Rhea Sumpter, +8

Proceedings of the National Academy of Sciences

Hepatitis C VirusImmunologyViral PathogenesisInnate ImmunityRetinoic Acid-inducible Gene +14

Autophagy Protects against Sindbis Virus Infection of the Central Nervous System

Anthony Orvedahl, Sarah MacPherson, Rhea Sumpter, +3

Cell Host & Microbe

Cell AutophagyMolecular VirologyPathogenesisAutophagyViral Pathogenesis +10

EGFR-Mediated Beclin 1 Phosphorylation in Autophagy Suppression, Tumor Progression, and Tumor Chemoresistance

Yongjie Wei, Zhongju Zou, Nils Becker, +12

Cell

Egfr-mediated Beclin 1Tumor BiologyTumor ChemoresistanceCell AutophagyMedicine +9

Image-based genome-wide siRNA screen identifies selective autophagy factors

Anthony Orvedahl, Rhea Sumpter, Guanghua Xiao, +14

Nature

Cell AutophagyMitophagyFunctional GenomicsAutophagy FactorsAutoantibody Production +5

Disruption of hepatitis C virus RNA replication through inhibition of host protein geranylgeranylation

Jin Ye, Chunfu Wang, Rhea Sumpter, +3

Proceedings of the National Academy of Sciences

Viral ReplicationMolecular VirologyBiochemistryHepatitis C VirusViral Hepatitis +11