Cell · 1992 · 1.1K citations · 40 references
Life SciencesImmunologyOncologyCancer ImmunologyImmunotherapyTumor ImmunologyAntitumor T Cell ResponsesCancer ImmunotherapyCell-mediated ImmunityCytotoxic T Lymphocyte ResponsesT Cell ActivationT Cell BiologyAdaptive Antitumor ImmunityB7 Family Immunoregulatory LigandsCd28 CostimulationCd28 SignalingCtla-4-mediated RegulationCytotoxic T-lymphocyte Antigen 4 (Ctla-4) PathwayT-cell Immune Responses
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CTLA-4 is a second receptor for the B cell activation antigen B7.
Peter S. Linsley, William Brady, M Urnes et al. · The Journal of Experimental Medicine · 1991 · 1.7K citations · Full text
A Theory of Self-Nonself Discrimination
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