Concepedia

Surface charge and hydrophobicity determine ErbB2 binding to the Hsp90 chaperone complex

Wanping Xu, Xitong Yuan, Zhexin Xiang, Edward G. Mimnaugh, Monica G. Marcu, Len Neckers

Nature Structural & Molecular Biology · 2005 · 154 citations · 37 references

DOI

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References

37

Human Breast Cancer: Correlation of Relapse and Survival with Amplification of the HER-2/<i>neu</i>Oncogene

Dennis J. Slamon, Gary M. Clark, Steven Wong et al. · Science · 1987 · 11.7K citations

, , +14

Protein folding and association: Insights from the interfacial and thermodynamic properties of hydrocarbons

Anthony Nicholls, Kim A. Sharp, Barry Honig · Proteins Structure Function and Bioinformatics · 1991 · 5.2K citations

, , +17

Structure of the Epidermal Growth Factor Receptor Kinase Domain Alone and in Complex with a 4-Anilinoquinazoline Inhibitor

Jennifer L. Stamos, Mark X. Sliwkowski, Charles Eigenbrot · Journal of Biological Chemistry · 2002 · 1.5K citations · Full text

, , +16

Crystal Structure of an Hsp90–Geldanamycin Complex: Targeting of a Protein Chaperone by an Antitumor Agent

C. Erec Stebbins, Alicia A. Russo, Christine Schneider et al. · Cell · 1997 · 1.4K citations · Full text

, , +17

A mechanism for hormone-independent prostate cancer through modulation of androgen receptor signaling by the HER-2/neu tyrosine kinase

Noah Craft, Yuriy Shostak, Michael Carey et al. · Nature Medicine · 1999 · 984 citations

, , +15