Wanping Xu

Chaperone-dependent E3 ubiquitin ligase CHIP mediates a degradative pathway for c-ErbB2/Neu

Wanping Xu, Monica G. Marcu, Xitong Yuan et al. · Proceedings of the National Academy of Sciences · 2002 · 430 citations

Life Sciences, Biochemistry, Molecular Biology +13

Sensitivity of Mature ErbB2 to Geldanamycin Is Conferred by Its Kinase Domain and Is Mediated by the Chaperone Protein Hsp90

Wanping Xu, Edward G. Mimnaugh, Meredith F.N. Rosser et al. · Journal of Biological Chemistry · 2001 · 353 citations · Full text

Medicine, Molecular Biology, Oncology +15

Molecular chaperone TRAP1 regulates a metabolic switch between mitochondrial respiration and aerobic glycolysis

Soichiro Yoshida, Shinji Tsutsumi, Guillaume Mühlebach et al. · Proceedings of the National Academy of Sciences · 2013 · 300 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +15

Simultaneous inhibition of hsp 90 and the proteasome promotes protein ubiquitination, causes endoplasmic reticulum-derived cytosolic vacuolization, and enhances antitumor activity

Edward G. Mimnaugh, Wanping Xu, Michele D. Vos et al. · Molecular Cancer Therapeutics · 2004 · 211 citations · Full text

Medicine, Oncology, Pharmacology +15

Threonine 22 Phosphorylation Attenuates Hsp90 Interaction with Cochaperones and Affects Its Chaperone Activity

Mehdi Mollapour, Shinji Tsutsumi, Andrew W. Truman et al. · Molecular Cell · 2011 · 166 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +11