Concepedia

Molecular Chaperones

Molecular Chaperones is a class of specialized proteins that facilitate the proper folding of other proteins by binding to non-native polypeptides and preventing misfolding or aggregation, thereby ensuring conformational maturation without being part of the final functional structure.

8.9K

Publications

686.9K

Citations

31K

Authors

4.1K

Institutions

Publications per year

2017–2026

1.7K

Variants

Chaperone Proteins

Parents

Children

Publications

8.9K

THE MAMMALIAN UNFOLDED PROTEIN RESPONSE

Martin Schröder, Randal J. Kaufman · Annual Review of Biochemistry · 2005 · 3K citations · Full text

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Chemical Chaperones Reduce ER Stress and Restore Glucose Homeostasis in a Mouse Model of Type 2 Diabetes

Umut Özcan, Erkan Yılmaz, Lale Özcan et al. · Science · 2006 · 2.4K citations · Full text

, , +17

Alpha-crystallin can function as a molecular chaperone.

Joseph Horwitz · Proceedings of the National Academy of Sciences · 1992 · 1.8K citations · Full text

, , +15

Sigma-1 Receptor Chaperones at the ER- Mitochondrion Interface Regulate Ca2+ Signaling and Cell Survival

Teruo Hayashi, Tsung‐Ping Su · Cell · 2007 · 1.8K citations · Full text

, , +14

A high-affinity conformation of Hsp90 confers tumour selectivity on Hsp90 inhibitors

Adeela Kamal, Lia Thao, John Sensintaffar et al. · Nature · 2003 · 1.4K citations

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1–5 of 8.9K

Authors

31K

  1. JB
    Johannes Büchner

    Technical University of Munich, Germany

    130 publications · 17.7K citations

    73

    h-index

  2. BB
    Bernd Bukau

    Heidelberg University, Germany

    97 publications · 16.9K citations

    72

    h-index

  3. FU
    F. Ulrich Hartl

    Max Planck Institute of Biochemistry, Germany

    105 publications · 21.5K citations

    68

    h-index

  4. JF
    Judith Frydman

    Stanford University, United States

    62 publications · 8.5K citations

    43

    h-index

  5. EA
    Elizabeth A. Craig

    University of Wisconsin–Madison, United States

    53 publications · 4.9K citations

    39

    h-index

1–5 of 31K

Institutions

4.1K

  1. Howard Hughes Medical Institute

    Chevy Chase, United States

    119 h-index

    704 publications

    147.4K citations

  2. University of Michigan

    Ann Arbor, United States

    81 h-index

    732 publications

    79.5K citations

  3. National Institutes of Health

    Bethesda, United States

    80 h-index

    786 publications

    76.3K citations

  4. Heidelberg University

    Heidelberg, Germany

    79 h-index

    582 publications

    77.4K citations

  5. Max Planck Institute of Biochemistry

    Martinsried, Germany

    73 h-index

    528 publications

    83.7K citations

  6. Stanford University

    Stanford, United States

    70 h-index

    431 publications

    43.3K citations

  7. University of Cambridge

    Cambridge, United Kingdom

    69 h-index

    553 publications

    53.6K citations

  8. Centre National de la Recherche Scientifique

    Paris, France

    68 h-index

    1.1K publications

    62.1K citations

1–8 of 4.1K

Venues

  1. Journal of Biological Chemistry

    JBC · 1.2K publications · 106.1K citations

    157

    h-index

  2. Proceedings of the National Academy of Sciences

    PNAS · 468 publications · 55.2K citations

    132

    h-index

  3. The EMBO Journal

    150 publications · 28.3K citations

    103

    h-index

  4. Molecular Cell

    114 publications · 19.8K citations

    86

    h-index

  5. Cell

    93 publications · 30.7K citations

    85

    h-index

1–5