Concepedia

Chaperone Substrate Specificity

Chaperone Substrate Specificity is the biochemical property that determines the selectivity of molecular chaperones for particular non-native protein substrates based on structural, sequence, or physicochemical features, distinguishing it from general chaperone activity by its targeted recognition and interaction with specific client proteins.

107

Publications

9.9K

Citations

551

Authors

206

Institutions

Publications per year

2017–2026

14

Parents

Publications

107

Substrate specificity of the DnaK chaperone determined by screening cellulose‐bound peptide libraries

Stefan Rüdiger, Lothar Germeroth, Jens Schneider‐Mergener et al. · The EMBO Journal · 1997 · 815 citations · Full text

, , +16

Peptide-binding specificity of the molecular chaperone BiP

Gregory C. Flynn, Jan Pohl, Mark T. Flocco et al. · Nature · 1991 · 773 citations

, , +14

Identification of in vivo substrates of the chaperonin GroEL

Walid A. Houry, Dmitrij Frishman, Christoph Eckerskorn et al. · Nature · 1999 · 504 citations

, , +9

GrpE‐like regulation of the Hsc70 chaperone by the anti‐apoptotic protein BAG‐1

J. Hohfeld · The EMBO Journal · 1997 · 398 citations · Full text

, , +15

Role of the ubiquitin‐selective CDC48UFD1/NPL4 chaperone (segregase) in ERAD of OLE1 and other substrates

Sigurd Braun, Kai Matuschewski, Michael Rapé et al. · The EMBO Journal · 2002 · 332 citations · Full text

, , +9

1–5 of 107

Authors

551

  1. BB
    Bernd Bukau

    Heidelberg University, Germany

    5 publications · 1.5K citations

    5

    h-index

  2. JB
    Johannes Büchner

    Technical University of Munich, Germany

    5 publications · 630 citations

    5

    h-index

  3. SR
    Stefan Rüdiger

    Utrecht University, Netherlands

    5 publications · 1.7K citations

    5

    h-index

  4. JS
    Jens Schneider‐Mergener

    Charité - Universitätsmedizin Berlin, Germany

    4 publications · 1.3K citations

    4

    h-index

  5. TK
    Takaki Koide

    Waseda University, Japan

    3 publications · 141 citations

    3

    h-index

1–5 of 551

Institutions

206

  1. National Institutes of Health

    Bethesda, United States

    6 h-index

    14 publications

    549 citations

  2. Howard Hughes Medical Institute

    Chevy Chase, United States

    6 h-index

    11 publications

    1.6K citations

  3. Max Planck Institute of Biochemistry

    Martinsried, Germany

    5 h-index

    13 publications

    3.9K citations

  4. Technical University of Munich

    Munich, Germany

    5 h-index

    25 publications

    2.4K citations

  5. University of Freiburg

    Freiburg im Breisgau, Germany

    5 h-index

    12 publications

    2.1K citations

  6. Heidelberg University

    Heidelberg, Germany

    5 h-index

    21 publications

    6.4K citations

  7. University of California, San Francisco

    San Francisco, United States

    4 h-index

    13 publications

    1.4K citations

  8. Japan Science and Technology Agency

    Tokyo, Japan

    4 h-index

    8 publications

    545 citations

1–8 of 206

Venues

  1. Journal of Biological Chemistry

    JBC · 19 publications · 1.5K citations

    19

    h-index

  2. Journal of Molecular Biology

    JMB · 9 publications · 437 citations

    9

    h-index

  3. The EMBO Journal

    6 publications · 2.1K citations

    6

    h-index

  4. Biochemical and Biophysical Research Communications

    BBRC · 6 publications · 309 citations

    6

    h-index

  5. Nature Structural & Molecular Biology

    4 publications · 605 citations

    4

    h-index

1–5