Charles Eigenbrot

Structure of the Epidermal Growth Factor Receptor Kinase Domain Alone and in Complex with a 4-Anilinoquinazoline Inhibitor

Jennifer L. Stamos, Mark X. Sliwkowski, Charles Eigenbrot · Journal of Biological Chemistry · 2002 · 1.5K citations · Full text

Diverse somatic mutation patterns and pathway alterations in human cancers

Zhengyan Kan, Bijay S. Jaiswal, Jeremy Stinson et al. · Nature · 2010 · 1K citations

Cancer Research, Engineering, Pathway Alterations +10

Conjugation site modulates the in vivo stability and therapeutic activity of antibody-drug conjugates

Ben‐Quan Shen, Keyang Xu, Luna Liu et al. · Nature Biotechnology · 2012 · 977 citations

Immunoengineering, Immunology, Bioconjugation +8

<b>Endocytosis and Sorting of ErbB2 and the Site of Action of Cancer Therapeutics Trastuzumab and Geldanamycin</b>

Cary D. Austin, Ann M. De Mazière, Paul I. Pisacane et al. · Molecular Biology of the Cell · 2004 · 486 citations · Full text

Pathology, Surface Erbb2, Cancer Biology +20

Crystal Structure at 1.7 Å Resolution of VEGF in Complex with Domain 2 of the Flt-1 Receptor

Christian Wiesmann, Germaine Fuh, Hans W. Christinger et al. · Cell · 1997 · 481 citations · Full text

Crystal Structure, Signal Transduction, Signaling Pathway +9