<b>Endocytosis and Sorting of ErbB2 and the Site of Action of Cancer Therapeutics Trastuzumab and Geldanamycin</b>

Cary D. Austin, Ann M. De Mazière, Paul I. Pisacane, +5

Molecular Biology of the Cell

PathologySurface Erbb2Cancer BiologyTumor BiologyOncology +18

Localization of the AP-3 adaptor complex defines a novel endosomal exit site for lysosomal membrane proteins

Andrew A. Peden, Viola Oorschot, Boris A. Hesser, +3

The Journal of Cell Biology

Lysosomal Membrane ProteinsAp-3 Adaptor ComplexMolecular BiologyCytoskeletonCellular Physiology +17

Increased expression of immunoreactive thymic stromal lymphopoietin in patients with severe asthma

Aarti Shikotra, David F. Choy, Chandra Ohri, +11

Journal of Allergy and Clinical Immunology

AsthmaAllergyLung InflammationImmunologyImmunologic Disease +4

Phospholipase D Stimulates Release of Nascent Secretory Vesicles from the <i>trans</i>-Golgi Network

Ye-Guang Chen, Anirban Siddhanta, Cary D. Austin, +5

The Journal of Cell Biology

Protein SecretionCytoskeletonCellular PhysiologySecretory GranulesPld Activity +19

Therapeutic antibodies reveal Notch control of transdifferentiation in the adult lung

Daniel Lafkas, Amy L. Shelton, Cecilia Chiu, +20

Nature

Notch ControlInflammatory Lung DiseaseLung InflammationImmunologyPulmonary Physiology +11

Oxidizing potential of endosomes and lysosomes limits intracellular cleavage of disulfide-based antibody–drug conjugates

Cary D. Austin, Xiaohui Wen, Lewis Gazzard, +3

Proceedings of the National Academy of Sciences

On the role of the platelet membrane skeleton in mediating signal transduction. Association of GP IIb-IIIa, pp60c-src, pp62c-yes, and the p21ras GTPase-activating protein with the membrane skeleton.

Joan E.B. Fox, Lorraine Lipfert, Edward A. Clark, +3

Journal of Biological Chemistry

Molecular BiologyCytoskeletonMembrane SkeletonCellular PhysiologyEndocytic Pathway +20

Evidence that agonist-induced activation of calpain causes the shedding of procoagulant-containing microvesicles from the membrane of aggregating platelets

Joan E.B. Fox, Cary D. Austin, C C Reynolds, +1

Journal of Biological Chemistry

Agonist-induced ActivationCytoskeletonMicrovesicles ResultsProcoagulant-containing MicrovesiclesCellular Physiology +19

In vivo blockade of OX40 ligand inhibits thymic stromal lymphopoietin driven atopic inflammation

Dhaya Seshasayee, Wyne P. Lee, Meijuan Zhou, +18

Journal of Clinical Investigation

AsthmaInflammatory Lung DiseaseVivo BlockadeAllergy MedicineImmune Regulation +15

Function of CSF1 and IL34 in Macrophage Homeostasis, Inflammation, and Cancer

WeiYu Lin, Daqi Xu, Cary D. Austin, +45

Frontiers in Immunology