Concepedia

Cryopreserved human hepatocytes in suspension are a convenient high throughput tool for the prediction of metabolic clearance

Delphine Jouin, Nadège Blanchard, Eliane Alexandre, Frédéric Delobel, Pascale David‐Pierson, Thierry Lavé, Daniel Jaeck, Lysiane Richert, Philippe Coassolo

European Journal of Pharmaceutics and Biopharmaceutics · 2006 · 36 citations · 24 references

DOI

Concepts

References

24

Effects of Prototypical Microsomal Enzyme Inducers on Cytochrome P450 Expression in Cultured Human Hepatocytes

Ajay Madan, Richard Graham, Kathleen Carroll et al. · Drug Metabolism and Disposition · 2003 · 337 citations

, , +17

Midazolam kinetics

Hannu Allonen, G. Ziegler, Ulrich Klotz · Clinical Pharmacology & Therapeutics · 1981 · 288 citations

, , +12

The pharmacokinetics of midazolam in man

Maree T. Smith, Mervyn J. Eadie, T. O'Rourke Brophy · European Journal of Clinical Pharmacology · 1981 · 280 citations

, , +7

EVALUATION OF FRESH AND CRYOPRESERVED HEPATOCYTES AS IN VITRO DRUG METABOLISM TOOLS FOR THE PREDICTION OF METABOLIC CLEARANCE

Dermot F. McGinnity, Matthew G. Soars, Richard A. Urbanowicz et al. · Drug Metabolism and Disposition · 2004 · 268 citations

, , +17

The pharmacokinetics of diclofenac sodium following intravenous and oral administration

J. V. Willis, M. J. Kendall, R. M. Flinn et al. · European Journal of Clinical Pharmacology · 1979 · 267 citations

, , +9