Richard Graham

Efficacy and Safety of Vismodegib in Advanced Basal-Cell Carcinoma

Aleksandar Sekulić, Michael R. Migden, Anthony E. Oro et al. · New England Journal of Medicine · 2012 · 1.4K citations · Full text

Medicine, Oncology, Pharmacology +17

Phase I Trial of Hedgehog Pathway Inhibitor Vismodegib (GDC-0449) in Patients with Refractory, Locally Advanced or Metastatic Solid Tumors

Patricia LoRusso, Charles M. Rudin, Josina C. Reddy et al. · Clinical Cancer Research · 2011 · 547 citations · Full text

Medicine, Oncology, Pharmacology +17

CYP3A4 Induction by Drugs: Correlation between a Pregnane X Receptor Reporter Gene Assay and CYP3A4 Expression in Human Hepatocytes

Gang Luo, Mark R. Cunningham, Sean Kim et al. · Drug Metabolism and Disposition · 2002 · 447 citations

Medicine, Pharmacology, Biochemical Pharmacology +15

Effects of Prototypical Microsomal Enzyme Inducers on Cytochrome P450 Expression in Cultured Human Hepatocytes

Ajay Madan, Richard Graham, Kathleen Carroll et al. · Drug Metabolism and Disposition · 2003 · 337 citations

Medicine, Biochemistry, Pharmacology +17

Engineered Thio-Trastuzumab-DM1 Conjugate with an Improved Therapeutic Index to Target Human Epidermal Growth Factor Receptor 2–Positive Breast Cancer

Jagath R. Junutula, Kelly M. Flagella, Richard Graham et al. · Clinical Cancer Research · 2010 · 292 citations

Pharmacy, Medicinal Chemistry, Oncology +17