PhRMA CPCDC initiative on predictive models of human pharmacokinetics, part 3: Comparative assessement of prediction methods of human clearance

Barbara J. Ring, Jenny Y. Chien, Kimberly K. Adkison, +15

Journal of Pharmaceutical Sciences

Pharmacokinetic ModelingMedicineDrug DiscoveryPrediction MethodsPhrma Cpcdc Initiative +6

PHRMA CPCDC initiative on predictive models of human pharmacokinetics, part 5: Prediction of plasma concentration–time profiles in human by using the physiologically‐based pharmacokinetic modeling approach

Patrick Poulin, Rhys D.O. Jones, Hannah M. Jones, +15

Journal of Pharmaceutical Sciences

Precision DosingPhysiologically Based PharmacokineticsPharmacokinetic ModelingHuman PharmacokineticsMedicine +7

Prediction of intestinal absorption: comparative assessment of gastroplus™ and idea™

Neil Parrott, Thierry Lavé

European Journal of Pharmaceutical Sciences

NutritionFunctional Gastrointestinal DisorderFood DigestionPhysiologyGastroenterology +4

Influence of molecular size on tissue distribution of antibody fragments

Zhe Li, Ben‐Fillippo Krippendorff, Sharad Sharma, +3

mAbs

Biodistribution CoefficientsImmunocytochemical TechniqueImmunologyPathologyImmunodominance +19

PhRMA CPCDC initiative on predictive models of human pharmacokinetics, part 2: Comparative assessment of prediction methods of human volume of distribution

Rhys D.O. Jones, Hannah M. Jones, Malcolm Rowland, +15

Journal of Pharmaceutical Sciences

Translational MedicinePharmacokinetic ModelingPart 2Prediction MethodsMedicine +9

Applications of Physiologically Based Absorption Models in Drug Discovery and Development

Neil Parrott, Thierry Lavé

Molecular Pharmaceutics

Pharmaceutical ResearchPhysiologically-based Pharmacokinetic ModelingPharmacological StudyBioanalysisAnalytical Chemistry +16

Challenges and opportunities with modelling and simulation in drug discovery and drug development

Thierry Lavé, Neil Parrott, Hans Peter Grimm, +2

Xenobiotica

Development of a Physiologically Based Model for Oseltamivir and Simulation of Pharmacokinetics in Neonates and Infants

Neil Parrott, Brian E. Davies, Gerhard Hoffmann, +5

Clinical Pharmacokinetics

Health SciencesPharmacodynamicsPharmacological StudyMedicinePhysiology +5

An Evaluation of the Utility of Physiologically Based Models of Pharmacokinetics in Early Drug Discovery

Neil Parrott, Nicolas Paquereau, Philippe Coassolo, +1

Journal of Pharmaceutical Sciences

Physiologically Based PharmacokineticsPharmacokinetic ModelingPharmacodynamicsPreclinical Drug EvaluationMedicine +9

Metabolic Profiling of Human Long-Term Liver Models and Hepatic Clearance Predictions from In Vitro Data Using Nonlinear Mixed-Effects Modeling

Nicole A. Kratochwil, Christophe Meille, Stephen Fowler, +14

The AAPS Journal

Fatty Liver DiseasePhysiologically-based Pharmacokinetic ModelingMetabolic SyndromeMolecular PharmacologyBiostatistics +23