Isolation and Culture of Primary Human Hepatocytes

Edward L. LeCluyse, Eliane Alexandre, Geraldine A. Hamilton, +4

Humana Press eBooks

PathologyCell CultureSpecies DifferencesHepatobiliary TumorHepatotoxicity +18

Isolation and Culture of Primary Hepatocytes from Resected Human Liver Tissue

Edward L. LeCluyse, Eliane Alexandre

Methods in molecular biology

Protective effects of N-acetylcysteine on hypothermic ischemia-reperfusion injury of rat liver

Hiroshi Nakano, Karim Boudjéma, Eliane Alexandre, +5

Hepatology

Lipid PeroxidationLiver FunctionOxidative StressInflammationHepatotoxicity +20

A multicenter assessment of single-cell models aligned to standard measures of cell health for prediction of acute hepatotoxicity

Rowena Sison‐Young, Volker M. Lauschke, Esther Johann, +20

Archives of Toxicology

Cell HealthImmunologyPathologyToxicological MechanismNew Drug +23

Comparative Proteomic Characterization of 4 Human Liver-Derived Single Cell Culture Models Reveals Significant Variation in the Capacity for Drug Disposition, Bioactivation, and Detoxication

Rowena Sison‐Young, Dimitra Mitsa, Rosalind E. Jenkins, +12

Toxicological Sciences

Drug DispositionCell CultureNew DrugSingle Cell SequencingHepatotoxicity +22

Comparison of the Effects of Various Peroxisome Proliferators on Peroxisomal Enzyme Activities, DNA Synthesis, and Apoptosis in Rat and Human Hepatocyte Cultures

Valérie Goll, Eliane Alexandre, Catherine Viollon‐Abadie, +3

Toxicology and Applied Pharmacology

Various Peroxisome ProliferatorsHepatologyBiochemistryMedicineLiver Physiology +11

Tissue collection, transport and isolation procedures required to optimize human hepatocyte isolation from waste liver surgical resections. A multilaboratory study

Lysiane Richert, Eliane Alexandre, Tom Lloyd, +9

Liver International

Hepatocyte ploidy in normal young rat

Arnaud Gandillet, Eliane Alexandre, Vincent Holl, +6

Comparative Biochemistry and Physiology Part A Molecular & Integrative Physiology

HepatologyBiliary TractLiver PhysiologyPhysiologyHistopathology +6

Plateable cryopreserved human hepatocytes for the assessment of cytochrome P450 inducibility: experimental condition-related variables affecting their response to inducers

Eliane Alexandre, Audrey Baze, C. Parmentier, +8

Xenobiotica

Cryopreserved human hepatocytes in suspension are a convenient high throughput tool for the prediction of metabolic clearance

Delphine Jouin, Nadège Blanchard, Eliane Alexandre, +6

European Journal of Pharmaceutics and Biopharmaceutics

Systems BiologyLiverHepatologyLiver PhysiologyPhysiology +13