Edward L. LeCluyse - Concepedia

Author

Edward L. LeCluyse

University of North Carolina at Chapel Hill ORCID

Also Known As

E L LeCluyse, E L Lecluyse, E LECLUYSE, E LeCluyse, E. L. LeCluyse, E. L. Lecluyse, E. LECLUYSE, E. LeCLUYSE, E. LeCluyse, E. Lecluyse

166

Publications

15.7K

Citations

H-Index

162

Concepts

All Affiliations

University of North Carolina at Chapel Hill Research Triangle Park Foundation The Hamner Institutes for Health Sciences University of Kansas Environmental Protection Agency

About

Edward L. LeCluyse is an author at University of North Carolina at Chapel Hill specializing in medicine, liver physiology, and hepatology.

Top Concepts

#	Concept	H-Index	Publications	Citations
1	Medicine	35	54	5.6K
2	Natural Sciences	14	14	1.9K
3	Health Sciences	10	10	701
4	Engineering	6	6	287
5	Public Health	2	2	301

Edward L. LeCluyse

105

Publications

11.9K

Citations

H-Index

Page 1

	Year	Citations
Comparative toxicity of trivalent and pentavalent inorganic and methylated arsenicals in rat and human cells Miroslav Stýblo, Luz M. Del Razo, Libia Vega, Archives of Toxicology Inorganic ChemistryBiochemistryHuman CellsMedicineMetalloid Contamination	2000	988
The Pregnane X Receptor: A Promiscuous Xenobiotic Receptor That Has Diverged during Evolution Stacey A. Jones, Linda B. Moore, Jennifer L. Shenk, Molecular Endocrinology Human PxrGeneticsReproductive BiologyExperimental PharmacologyTranslational Pharmacology	2000	557
<i>In vitro</i> models for liver toxicity testing. Valerie Y. Soldatow, Edward L. LeCluyse, Linda G. Griffith, PubMed	2013	448
CYP3A4 Induction by Drugs: Correlation between a Pregnane X Receptor Reporter Gene Assay and CYP3A4 Expression in Human Hepatocytes Gang Luo, Mark R. Cunningham, Sean Kim, Drug Metabolism and Disposition	2002	446
Validation of Bupropion Hydroxylation as a Selective Marker of Human Cytochrome P450 2B6 Catalytic Activity Stephanie Faucette, Roy L. Hawke, Edward L. LeCluyse, Drug Metabolism and Disposition	2000	355
Effects of Prototypical Microsomal Enzyme Inducers on Cytochrome P450 Expression in Cultured Human Hepatocytes Ajay Madan, Richard Graham, Kathleen Carroll, Drug Metabolism and Disposition	2003	337
Relative Activation of Human Pregnane X Receptor versus Constitutive Androstane Receptor Defines Distinct Classes of CYP2B6 and CYP3A4 Inducers Stephanie Faucette, Tong-Cun Zhang, Rick Moore, Journal of Pharmacology and Experimental Therapeutics	2006	288
Anti-Influenza Prodrug Oseltamivir Is Activated by Carboxylesterase Human Carboxylesterase 1, and the Activation Is Inhibited by Antiplatelet Agent Clopidogrel Deshi Shi, Jian Yang, Dongfang Yang, Journal of Pharmacology and Experimental Therapeutics	2006	273
Formation of extensive canalicular networks by rat hepatocytes cultured in collagen-sandwich configuration Edward L. LeCluyse, Kenneth L. Audus, Jerome Hochman American Journal of Physiology-Cell Physiology Tissue EngineeringRat Primary HepatocytesSandwich ConfigurationCell CultureCytoskeleton	1994	260
Antiplatelet Agents Aspirin and Clopidogrel Are Hydrolyzed by Distinct Carboxylesterases, and Clopidogrel Is Transesterificated in the Presence of Ethyl Alcohol Man Tang, Madhu Mukundan, Jian Yang, Journal of Pharmacology and Experimental Therapeutics	2006	248

Page 1