2-Trifluoroacetylthiophenes, a novel series of potent and selective class II histone deacetylase inhibitors

HDAC6 is a microtubule-associated deacetylase

Charlotte Hubbert, Amaris R. Guardiola, Rong Shao et al. · Nature · 2002 · 2.3K citations

Biochemistry, Natural Sciences, Microtubule-associated Deacetylase +4

Structures of a histone deacetylase homologue bound to the TSA and SAHA inhibitors

Michael S. Finnin, Jill R. Donigian, Alona Cohen et al. · Nature · 1999 · 1.7K citations

Histone Modifications, Chromatin, Chromatin Structure +11

Unraveling the hidden catalytic activity of vertebrate class IIa histone deacetylases

Armin Lahm, Chantal Paolini, Michele Pallaoro et al. · Proceedings of the National Academy of Sciences · 2007 · 569 citations · Full text

Histone Modifications, Hdac Inhibitors, Epigenetic Change +18

Probing the elusive catalytic activity of vertebrate class IIa histone deacetylases

Philip Jones, Sergio Altamura, Raffaele De Francesco et al. · Bioorganic & Medicinal Chemistry Letters · 2008 · 99 citations · Full text

Histone Modifications, Chromatin, Biochemistry +9