Ottavia Cecchetti

Inhibiting pathologically active ADAM10 rescues synaptic and cognitive decline in Huntington’s disease

Elena Vezzoli, Ilaria Caron, Francesca Talpo et al. · Journal of Clinical Investigation · 2019 · 97 citations · Full text

A series of novel, potent, and selective histone deacetylase inhibitors

Philip Jones, Sergio Altamura, Prasun K. Chakravarty et al. · Bioorganic & Medicinal Chemistry Letters · 2006 · 66 citations · Full text

Histone Modifications, Chromatin, Medicinal Chemistry +8

2-Trifluoroacetylthiophenes, a novel series of potent and selective class II histone deacetylase inhibitors

Philip Jones, Matthew J. Bottomley, Ottavia Cecchetti et al. · Bioorganic & Medicinal Chemistry Letters · 2008 · 64 citations · Full text

Medicinal Chemistry, Novel Series, Medicine +6

2-Trifluoroacetylthiophene oxadiazoles as potent and selective class II human histone deacetylase inhibitors

Ester Muraglia, Sergio Altamura, Danila Branca et al. · Bioorganic & Medicinal Chemistry Letters · 2008 · 53 citations · Full text

Medicinal Chemistry, Biochemistry, Medicine +10

Discovery of a Selective Series of Inhibitors of <i>Plasmodium falciparum</i> HDACs

Jesus M. Ontoria, Giacomo Paonessa, Simona Ponzi et al. · ACS Medicinal Chemistry Letters · 2016 · 40 citations · Full text

Antiparasitic Agent, Malaria, Pharmacotherapy +17