Concepedia

The Hsc70 co-chaperone CHIP targets immature CFTR for proteasomal degradation

Geoffrey C. Meacham, Cam Patterson, Wenyue Zhang, J. Michael Younger, Douglas Cyr

Nature Cell Biology · 2000 · 837 citations · 33 references

DOI

Concepts

References

33

Identification of the Cystic Fibrosis Gene: Cloning and Characterization of Complementary DNA

John R. Riordan, Johanna M. Rommens, Bat-Sheva Kerem et al. · Science · 1989 · 7.4K citations

, , +12

Aggresomes: A Cellular Response to Misfolded Proteins

Jennifer Johnston, Cristina L. Ward, Ron R. Kopito · The Journal of Cell Biology · 1998 · 2.2K citations · Full text

, , +17

Defective intracellular transport and processing of CFTR is the molecular basis of most cystic fibrosis

Seng H. Cheng, Richard J. Gregory, John Marshall et al. · Cell · 1990 · 1.8K citations

, , +12

Degradation of CFTR by the ubiquitin-proteasome pathway

Cristina L. Ward, Satoshi ŌMURA, Ron R. Kopito · Cell · 1995 · 1.3K citations · Full text

, , +17

A Novel Ubiquitination Factor, E4, Is Involved in Multiubiquitin Chain Assembly

Manfred Koegl, Thorsten Hoppe, Stephan Schlenker et al. · Cell · 1999 · 1.1K citations · Full text

, , +7