Concepedia

Douglas Cyr

DC

Statistics

Publications

69

Citations

8.2K

H-Index

44

Active since

1986

Affiliations

University of North Carolina at Chapel Hill(Current)

Universidade Estadual de Campinas (UNICAMP)

University of Rhode Island

University of Alabama

University of Alabama at Birmingham

Douglas Cyr is an author at University of North Carolina at Chapel Hill specializing in medicine, natural sciences, and molecular biology.

Top concepts

MedicineNatural SciencesMolecular BiologyBiochemistryCell BiologyCellular BiochemistryProtein FoldingProteomicsSignal TransductionCell Signaling

Publications per year

1986–2024

69

Publications

69

The Hsc70 co-chaperone CHIP targets immature CFTR for proteasomal degradation

Geoffrey C. Meacham, Cam Patterson, Wenyue Zhang et al. · Nature Cell Biology · 2000 · 832 citations

Proteomic Technology, Protein Function, Biochemistry +10

From CFTR biology toward combinatorial pharmacotherapy: expanded classification of cystic fibrosis mutations

Radu G. Avramescu, Annette Chiang, Scott A. Houck et al. · Molecular Biology of the Cell · 2016 · 582 citations · Full text

Pathology, Combinatorial Pharmacotherapy, Synaptic Signaling +28

Sequential Quality-Control Checkpoints Triage Misfolded Cystic Fibrosis Transmembrane Conductance Regulator

J. Michael Younger, Liling Chen, Hong-Yu Ren et al. · Cell · 2006 · 432 citations · Full text

Protein Quality Control, Signal Transduction, Pathology +3

CHIP-mediated stress recovery by sequential ubiquitination of substrates and Hsp70

Shu-Bing Qian, Holly McDonough, Frank Boellmann et al. · Nature · 2006 · 365 citations · Full text

Chromatin, Chip-mediated Stress Recovery, Molecular Biology +1

Protein quality control: U-box-containing E3 ubiquitin ligases join the fold

Douglas Cyr, Jörg Höhfeld, Cam Patterson · Trends in Biochemical Sciences · 2002 · 341 citations

Protein Chemistry, Protein Quality Control, Protein Function +8

1–5 of 69