Temporary depletion of complement component C3 or genetic deficiency of C1q significantly delays onset of scrapie

Normal development and behaviour of mice lacking the neuronal cell-surface PrP protein

Hansruedi Büeler, Marek Fischer, Yolande Lang et al. · Nature · 1992 · 1.7K citations · Full text

Life Sciences, Neurobiology, Neuroscience +13

Homozygous C1q deficiency causes glomerulonephritis associated with multiple apoptotic bodies

Marina Botto, Chiara Dell' Agnola, Anne E. Bygrave et al. · Nature Genetics · 1998 · 1.4K citations

Medicine, Immunology, Nephrology +14

Identification of a Protein That Purifies with the Scrapie Prion

David C. Bolton, Michael P. McKinley, Stanley B. Prusiner · Science · 1982 · 1.3K citations

Life Sciences, Biochemistry, Molecular Biology +14

Investigation of variant Creutzfeldt-Jakob disease and other human prion diseases with tonsil biopsy samples

R J Butterworth, Sarah Joiner, Graham S. Jackson et al. · The Lancet · 1999 · 702 citations

Veterinary Medicine, Genetics, Pathology +15

Further purification and characterization of scrapie prions

Stanley B. Prusiner, David C. Bolton, Darlene Groth et al. · Biochemistry · 1982 · 464 citations

Veterinary Medicine, Biochemistry, Bioseparations +13