Concepedia

Complement Disorders

Complement Disorders is a class of immunological conditions characterized by deficiencies or dysregulation in the complement system, a key component of innate immunity, that lead to increased susceptibility to infections, autoimmune manifestations, or inflammatory pathologies.

2.4K

Publications

132.5K

Citations

10.3K

Authors

2.3K

Institutions

Publications per year

2017–2026

366

Variants

Complement System Disorders

Parents

Children

Publications

2.4K

Terminal Complement Inhibitor Eculizumab in Atypical Hemolytic–Uremic Syndrome

Christophe Legendre, Christoph Licht, Petra Muus et al. · New England Journal of Medicine · 2013 · 1.6K citations · Full text

, , +17

The Complement Inhibitor Eculizumab in Paroxysmal Nocturnal Hemoglobinuria

Peter Hillmen, Neal S. Young, Jörg Schubert et al. · New England Journal of Medicine · 2006 · 1.3K citations · Full text

, , +17

Relative Role of Genetic Complement Abnormalities in Sporadic and Familial aHUS and Their Impact on Clinical Phenotype

Marina Noris, Jessica Caprioli, Elena Bresin et al. · Clinical Journal of the American Society of Nephrology · 2010 · 1K citations · Full text

, , +13

Eculizumab in Aquaporin-4–Positive Neuromyelitis Optica Spectrum Disorder

Sean J. Pittock, Achim Berthele, Kazuo Fujihara et al. · New England Journal of Medicine · 2019 · 846 citations · Full text

, , +17

Discovery and development of the complement inhibitor eculizumab for the treatment of paroxysmal nocturnal hemoglobinuria

Russell P. Rother, Scott A. Rollins, Christopher F. Mojcik et al. · Nature Biotechnology · 2007 · 764 citations

, , +13

1–5 of 2.4K

Authors

10.3K

  1. VF
    Véronique Frémeaux‐Bacchi

    Hôpital Européen Georges-Pompidou, France

    68 publications · 8.9K citations

    47

    h-index

  2. SR
    Santiago Rodrı́guez de Córdoba

    Centro de Investigaciones Biológicas Margarita Salas, Spain

    39 publications · 3.9K citations

    30

    h-index

  3. TH
    Timothy H.J. Goodship

    Newcastle University, United Kingdom

    32 publications · 4.8K citations

    27

    h-index

  4. FS
    Fred S. Rosen

    Harvard University, United States

    26 publications · 3.4K citations

    26

    h-index

  5. MN
    Marina Noris

    Mario Negri Institute for Pharmacological Research, Italy

    27 publications · 4.7K citations

    24

    h-index

1–5 of 10.3K

Institutions

2.3K

  1. Inserm

    Paris, France

    45 h-index

    263 publications

    30.5K citations

  2. Hôpital Européen

    Marseille, France

    45 h-index

    151 publications

    28.1K citations

  3. Hôpital Européen Georges-Pompidou

    Paris, France

    43 h-index

    153 publications

    25.7K citations

  4. Assistance Publique – Hôpitaux de Paris

    Paris, France

    42 h-index

    180 publications

    20.9K citations

  5. Newcastle University

    Newcastle upon Tyne, United Kingdom

    38 h-index

    184 publications

    15.7K citations

  6. Harvard University

    Cambridge, United States

    38 h-index

    177 publications

    18K citations

  7. Centre de Recherche des Cordeliers

    Paris, France

    35 h-index

    153 publications

    20.3K citations

  8. Lund University

    Lund, Sweden

    33 h-index

    204 publications

    9.3K citations

1–8 of 2.3K

Venues

  1. Journal of Clinical Investigation

    JCI · 77 publications · 7.2K citations

    54

    h-index

  2. PubMed

    Repository · 311 publications · 11.6K citations

    53

    h-index

  3. The Journal of Immunology

    JI · 96 publications · 5.1K citations

    42

    h-index

  4. Blood

    79 publications · 7K citations

    42

    h-index

  5. New England Journal of Medicine

    NEJM · 42 publications · 10.5K citations

    38

    h-index

1–5