Concepedia

Discovery and development of the complement inhibitor eculizumab for the treatment of paroxysmal nocturnal hemoglobinuria

Russell P. Rother, Scott A. Rollins, Christopher F. Mojcik, Robert A. Brodsky, Leonard Bell

Nature Biotechnology · 2007 · 764 citations · 73 references

DOI

Concepts

References

73

Hematology: Basic Principles and Practice

Annals of Internal Medicine · 1991 · 1.9K citations

, , +17

Reshaping human antibodies for therapy

Lutz Riechmann, Herman Waldmann, Greg Winter · Nature · 1988 · 1.6K citations

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ENDOGENOUS NITRIC OXIDE INHIBITS HUMAN PLATELET ADHESION TO VASCULAR ENDOTHELIUM

Marek W. Radomski, Richard Palmer, Salvador Moncada · The Lancet · 1987 · 1.4K citations

, , +10

The Complement Inhibitor Eculizumab in Paroxysmal Nocturnal Hemoglobinuria

Peter Hillmen, Neal S. Young, Jörg Schubert et al. · New England Journal of Medicine · 2006 · 1.3K citations · Full text

, , +17

The anti‐aggregating properties of vascular endothelium: interactions between prostacyclin and nitric oxide

Marek W. Radomski, Richard Palmer, Salvador Moncada · British Journal of Pharmacology · 1987 · 1.2K citations · Full text

, , +17