Concepedia

Complement-mediated Injury

Complement-Mediated Injury is a form of tissue damage resulting from the inappropriate or excessive activation of the complement system, distinguishing it from other immune-mediated injuries by its reliance on complement proteins to induce inflammation, cell lysis, and opsonization in the absence of controlled regulatory mechanisms.

5.5K

Publications

325.2K

Citations

23.5K

Authors

3.6K

Institutions

Publications per year

2017–2026

841

Parents

Children

Publications

5.5K

Complement associated microvascular injury and thrombosis in the pathogenesis of severe COVID-19 infection: A report of five cases

Cynthia M. Magro, J. Justin Mulvey, David Berlin et al. · Translational research · 2020 · 2.3K citations · Full text

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Terminal Complement Inhibitor Eculizumab in Atypical Hemolytic–Uremic Syndrome

Christophe Legendre, Christoph Licht, Petra Muus et al. · New England Journal of Medicine · 2013 · 1.6K citations · Full text

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Complement and the damaging effects of cardiopulmonary bypass

James K. Kirklin, James K. Kirklin, Stephen Westaby et al. · Journal of Thoracic and Cardiovascular Surgery · 1983 · 1.3K citations

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The Complement Inhibitor Eculizumab in Paroxysmal Nocturnal Hemoglobinuria

Peter Hillmen, Neal S. Young, Jörg Schubert et al. · New England Journal of Medicine · 2006 · 1.3K citations · Full text

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Complement Activation during Cardiopulmonary Bypass

Dennis E. Chenoweth, Steven W. Cooper, Tony E. Hugli et al. · New England Journal of Medicine · 1981 · 1.2K citations

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1–5 of 5.5K

Authors

23.5K

  1. BP
    B. Paul Morgan

    Cardiff University, United Kingdom

    103 publications · 7.7K citations

    50

    h-index

  2. JD
    John D. Lambris

    University of Pennsylvania, United States

    80 publications · 9.2K citations

    48

    h-index

  3. VM
    V. Michael Holers

    University of Colorado Denver, United States

    71 publications · 7.9K citations

    45

    h-index

  4. TE
    Tom Eirik Mollnes

    Oslo University Hospital, Norway

    88 publications · 5.6K citations

    41

    h-index

  5. PA
    Peter A. Ward

    University of Michigan, United States

    61 publications · 5.4K citations

    41

    h-index

1–5 of 23.5K

Institutions

3.6K

  1. Harvard University

    Cambridge, United States

    64 h-index

    628 publications

    55.7K citations

  2. University of Pennsylvania

    Philadelphia, United States

    58 h-index

    384 publications

    38.7K citations

  3. University of Michigan

    Ann Arbor, United States

    54 h-index

    429 publications

    39.3K citations

  4. Brigham and Women's Hospital

    Boston, United States

    50 h-index

    427 publications

    46.1K citations

  5. University of Colorado Denver

    Denver, United States

    47 h-index

    311 publications

    22.1K citations

  6. Inserm

    Paris, France

    43 h-index

    428 publications

    32.7K citations

  7. Johns Hopkins University

    Baltimore, United States

    42 h-index

    280 publications

    27.2K citations

  8. University of Wales

    Cardiff, United Kingdom

    42 h-index

    194 publications

    16.2K citations

1–8 of 3.6K

Venues

  1. The Journal of Immunology

    JI · 288 publications · 19.4K citations

    80

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  2. PubMed

    Repository · 509 publications · 20.5K citations

    71

    h-index

  3. Journal of Clinical Investigation

    JCI · 109 publications · 17.5K citations

    68

    h-index

  4. The Journal of Experimental Medicine

    87 publications · 12.5K citations

    62

    h-index

  5. Blood

    107 publications · 11.8K citations

    58

    h-index

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