Concepedia

Terminal Complement Complex

The Terminal Complement Complex is a transmembrane pore-forming structure generated during the terminal phase of the complement cascade, distinguishing itself from other complement-derived products by mediating direct cytolysis through insertion into pathogen or host cell membranes.

628

Publications

40.5K

Citations

2.6K

Authors

713

Institutions

Publications per year

2017–2026

86

Parents

Publications

628

Complement associated microvascular injury and thrombosis in the pathogenesis of severe COVID-19 infection: A report of five cases

Cynthia M. Magro, J. Justin Mulvey, David Berlin et al. · Translational research · 2020 · 2.3K citations · Full text

, , +17

The Complement Inhibitor Eculizumab in Paroxysmal Nocturnal Hemoglobinuria

Peter Hillmen, Neal S. Young, Jörg Schubert et al. · New England Journal of Medicine · 2006 · 1.3K citations · Full text

, , +17

C-Reactive Protein Binds to Apoptotic Cells, Protects the Cells from Assembly of the Terminal Complement Components, and Sustains an Antiinflammatory Innate Immune Response

Debra Gershov, SunJung Kim, Nathan Brot et al. · The Journal of Experimental Medicine · 2000 · 695 citations · Full text

, , +17

Effect of Eculizumab on Hemolysis and Transfusion Requirements in Patients with Paroxysmal Nocturnal Hemoglobinuria

Peter Hillmen, Claire Hall, Judith Marsh et al. · New England Journal of Medicine · 2004 · 637 citations · Full text

, , +17

C-Reactive Protein Frequently Colocalizes With the Terminal Complement Complex in the Intima of Early Atherosclerotic Lesions of Human Coronary Arteries

Jan Torzewski, Michael Torzewski, David E. Bowyer et al. · Arteriosclerosis Thrombosis and Vascular Biology · 1998 · 564 citations

, , +17

1–5 of 628

Authors

2.6K

  1. TE
    Tom Eirik Mollnes

    Oslo University Hospital, Norway

    66 publications · 3.8K citations

    34

    h-index

  2. SB
    Sucharit Bhakdi

    Johannes Gutenberg University Mainz, Germany

    28 publications · 2.2K citations

    24

    h-index

  3. PG
    Peter Garred

    Rigshospitalet, Denmark

    25 publications · 1.3K citations

    18

    h-index

  4. BP
    B. Paul Morgan

    Cardiff University, United Kingdom

    21 publications · 1.2K citations

    18

    h-index

  5. HR
    Horea Rus

    University of Maryland, Baltimore, United States

    19 publications · 1.3K citations

    17

    h-index

1–5 of 2.6K

Institutions

713

  1. Oslo University Hospital

    Oslo, Norway

    29 h-index

    227 publications

    20.4K citations

  2. University of Oslo

    Oslo, Norway

    27 h-index

    214 publications

    16.1K citations

  3. Nordland Hospital

    Bodø, Norway

    23 h-index

    63 publications

    3.5K citations

  4. University of Maryland, Baltimore

    Baltimore, United States

    23 h-index

    89 publications

    6.4K citations

  5. Heidelberg University

    Heidelberg, Germany

    20 h-index

    65 publications

    2.5K citations

  6. Harvard University

    Cambridge, United States

    16 h-index

    58 publications

    6.4K citations

  7. Brigham and Women's Hospital

    Boston, United States

    16 h-index

    47 publications

    5.2K citations

  8. Norwegian University of Science and Technology

    Trondheim, Norway

    16 h-index

    43 publications

    1.7K citations

1–8 of 713

Venues

  1. The Journal of Immunology

    JI · 59 publications · 4K citations

    40

    h-index

  2. PubMed

    Repository · 47 publications · 1.9K citations

    28

    h-index

  3. Clinical & Experimental Immunology

    CEI · 27 publications · 1.2K citations

    20

    h-index

  4. Proceedings of the National Academy of Sciences

    PNAS · 17 publications · 2.2K citations

    17

    h-index

  5. Journal of Biological Chemistry

    JBC · 16 publications · 1.6K citations

    16

    h-index

1–5