Mutations in VKORC1 cause warfarin resistance and multiple coagulation factor deficiency type 2

Simone Rost, Andreas Fregin, Vytautas Ivaškevičius, +10

Nature

ThrombosisDisease MechanismGenetic DisorderMedicineGenetics +8

Prognostic Effect of Epithelial and Stromal Lymphocyte Infiltration in Non–Small Cell Lung Cancer

Khalid Al‐Shibli, Tom Dønnem, Samer Al‐Saad, +3

Clinical Cancer Research

2010 International consensus algorithm for the diagnosis, therapy and management of hereditary angioedema

Tom Bowen, Marco Cicardi, Henriette Farkas, +57

Allergy Asthma and Clinical Immunology

Incidence of Acute Nonperforated and Perforated Appendicitis: Age‐specific and Sex‐specific Analysis

Hartwig Kørner, Karl Søndenaa, Jon Arne Søreide, +4

World Journal of Surgery

Tenecteplase versus alteplase for management of acute ischaemic stroke (NOR-TEST): a phase 3, randomised, open-label, blinded endpoint trial

Nicola Logallo, Vojtěch Novotný, Christopher Elnan Kvistad, +17

The Lancet Neurology

ThrombosisEndpoint TrialTenecteplase Versus AlteplaseIschemic StrokeCardiovascular Disease +11

Systemic complement activation is associated with respiratory failure in COVID-19 hospitalized patients

Jan Cato Holter, Eline de Boer, Andreas Lind, +28

Proceedings of the National Academy of Sciences

Metformin Versus Placebo from First Trimester to Delivery in Polycystic Ovary Syndrome: A Randomized, Controlled Multicenter Study

Eszter Vanky, Solhild Stridsklev, Runa Heimstad, +16

The Journal of Clinical Endocrinology & Metabolism

Cholesterol Crystals Induce Complement-Dependent Inflammasome Activation and Cytokine Release

Eivind Ottersen Samstad, Nathalie Niyonzima, Stig Nymo, +10

The Journal of Immunology

International consensus and practical guidelines on the gynecologic and obstetric management of female patients with hereditary angioedema caused by C1 inhibitor deficiency

Teresa Caballero, Henriette Farkas, Laurence Bouillet, +16

Journal of Allergy and Clinical Immunology

Cardiovascular DiseaseC1 Inhibitor DeficiencyInternational ConsensusHematologyHereditary Angioedema +2

Hereditary porcine membranoproliferative glomerulonephritis type II is caused by factor H deficiency.

J. H. Jansen, Tom Eirik Mollnes, Jan Hovdenes, +1

Journal of Clinical Investigation

Glomerular DiseaseRenal PathologyImmunologyPathologyInflammation +19