Concepedia

Complement System Activation

Complement System Activation is a biochemical cascade process within the innate immune response that is distinguished by the sequential activation of complement proteins leading to pathogen opsonization, inflammation, and membrane attack complex formation in periodontal host defense.

4.4K

Publications

262.9K

Citations

19.4K

Authors

3.3K

Institutions

Publications per year

2017–2026

953

Parents

Publications

4.4K

Complement and microglia mediate early synapse loss in Alzheimer mouse models

Soyon Hong, Victoria F. Beja-Glasser, Bianca M. Nfonoyim et al. · Science · 2016 · 3.4K citations · Full text

, , +17

Lysozyme: an important defence molecule of fish innate immune system

Shailesh Saurabh, Pramoda Kumar Sahoo · Aquaculture Research · 2008 · 1.6K citations

, , +13

Soluble Human Complement Receptor Type 1: In Vivo Inhibitor of Complement Suppressing Post-Ischemic Myocardial Inflammation and Necrosis

Harlan F. Weisman, Michelle K. Leppo, Henry C. Marsh et al. · Science · 1990 · 979 citations

, , +17

Shotgun proteomics implicates protease inhibition and complement activation in the antiinflammatory properties of HDL

Tomáš Vaisar, Subramaniam Pennathur, Pattie S. Green et al. · Journal of Clinical Investigation · 2007 · 940 citations · Full text

, , +16

Human membrane cofactor protein (CD46) acts as a cellular receptor for measles virus

Denise Naniche, G Varior-Krishnan, F Cervoni et al. · Journal of Virology · 1993 · 851 citations · Full text

, , +17

1–5 of 4.4K

Authors

19.4K

  1. JD
    John D. Lambris

    University of Pennsylvania, United States

    72 publications · 6K citations

    43

    h-index

  2. AM
    Anna M. Blom

    Lund University, Sweden

    75 publications · 4.9K citations

    42

    h-index

  3. TE
    Tom Eirik Mollnes

    Oslo University Hospital, Norway

    86 publications · 4.9K citations

    39

    h-index

  4. ST
    Steffen Thiel

    Aarhus University, Denmark

    63 publications · 3.8K citations

    36

    h-index

  5. VM
    V. Michael Holers

    University of Colorado Denver, United States

    49 publications · 4.5K citations

    35

    h-index

1–5 of 19.4K

Institutions

3.3K

  1. Lund University

    Lund, Sweden

    53 h-index

    471 publications

    30.1K citations

  2. Harvard University

    Cambridge, United States

    50 h-index

    348 publications

    50.3K citations

  3. University of Pennsylvania

    Philadelphia, United States

    48 h-index

    300 publications

    24.1K citations

  4. University of Colorado Denver

    Denver, United States

    44 h-index

    278 publications

    17.8K citations

  5. Leiden University Medical Center

    Leiden, The Netherlands

    44 h-index

    276 publications

    26.1K citations

  6. Aarhus University

    Aarhus, Denmark

    41 h-index

    256 publications

    14.2K citations

  7. University of Oslo

    Oslo, Norway

    41 h-index

    304 publications

    20.9K citations

  8. University of Michigan

    Ann Arbor, United States

    39 h-index

    294 publications

    26.6K citations

1–8 of 3.3K

Venues

  1. The Journal of Immunology

    JI · 393 publications · 32K citations

    99

    h-index

  2. PubMed

    Repository · 347 publications · 14.5K citations

    61

    h-index

  3. The Journal of Experimental Medicine

    77 publications · 13.9K citations

    60

    h-index

  4. Infection and Immunity

    IAI · 165 publications · 9.6K citations

    58

    h-index

  5. Journal of Biological Chemistry

    JBC · 115 publications · 9.4K citations

    56

    h-index

1–5