Complement Factor H Deficiency is a rare genetic disorder characterized by impaired regulation of the alternative complement pathway due to mutations in the complement factor H protein, leading to uncontrolled complement activation and increased risk of autoimmune and inflammatory conditions such as atypical hemolytic uremic syndrome.
522
Publications
49.1K
Citations
3K
Authors
889
Institutions
Publications per year
2017–2026
101
Variants
Cfh Deficiency
Parents
Publications
522
Complement Factor H Polymorphism in Age-Related Macular Degeneration
Robert J. Klein, Caroline J. Zeiss, Emily Y. Chew et al. · Science · 2005 · 4.5K citations
Medicine, Immunology, Ophthalmology +14
Complement Factor H Polymorphism and Age-Related Macular Degeneration
Albert O. Edwards, Robert Ritter, Kenneth J. Abel et al. · Science · 2005 · 2.4K citations
Medicine, Immunology, Ophthalmology +14
Complement Factor H Variant Increases the Risk of Age-Related Macular Degeneration
Jonathan L. Haines, Michael A. Hauser, Silke Schmidt et al. · Science · 2005 · 2.4K citations
Medicine, Genetics, Ophthalmology +14
Gregory S. Hageman, Don H. Anderson, Lincoln V. Johnson et al. · Proceedings of the National Academy of Sciences · 2005 · 2K citations · Full text
Marina Noris, Jessica Caprioli, Elena Bresin et al. · Clinical Journal of the American Society of Nephrology · 2010 · 1K citations · Full text
1–5 of 522
Authors
3K
- VF
28
h-index
- PFPeter F. Zipfel
Leibniz-Institut für Naturstoff-Forschung und Infektionsbiologie e. V. - Hans-Knöll-Institut (HKI), Germany
32 publications · 4.4K citations
28
h-index
- SRSantiago Rodrı́guez de Córdoba
Centro de Investigaciones Biológicas Margarita Salas, Spain
24 publications · 2.6K citations
23
h-index
- MC
23
h-index
- TH
22
h-index
1–5 of 3K
Institutions
889
Leibniz-Institut für Naturstoff-Forschung und Infektionsbiologie e. V. - Hans-Knöll-Institut (HKI)
Jena, Germany
29 h-index
98 publications
13.8K citations
Newcastle University
Newcastle upon Tyne, United Kingdom
28 h-index
154 publications
19.9K citations
Hôpital Européen
Marseille, France
27 h-index
67 publications
18.9K citations
Hôpital Européen Georges-Pompidou
Paris, France
27 h-index
64 publications
17.3K citations
University College London
London, United Kingdom
22 h-index
95 publications
5.9K citations
Centro de Investigaciones Biológicas Margarita Salas
Madrid, Spain
20 h-index
62 publications
8.3K citations
University of Helsinki
Helsinki, Finland
20 h-index
66 publications
5.9K citations
Imperial College London
London, United Kingdom
19 h-index
73 publications
7.9K citations
1–8 of 889
Venues
- Journal of the American Society of Nephrology
32 publications · 4.5K citations
31
h-index
- Pediatric Nephrology
26 publications · 1.1K citations
20
h-index
- Investigative Ophthalmology & Visual Science
IOVS · 19 publications · 744 citations
17
h-index
- Kidney International
17 publications · 1.9K citations
16
h-index
- PubMed
Repository · 22 publications · 929 citations
15
h-index
1–5