Complement-mediated Disease

Complement-Med Disease is a pathological condition in which dysregulation or overactivation of the complement system directly contributes to tissue damage, inflammation, or immune dysfunction, distinguishing it from other immune-mediated disorders by its specific dependence on complement pathway effector mechanisms.

523

Publications

33.1K

Citations

2.9K

Authors

923

Institutions

Publications per year

2017–2026

114

Parents

Complement Disorders

Publications

523

Terminal Complement Inhibitor Eculizumab in Atypical Hemolytic–Uremic Syndrome

Christophe Legendre, Christoph Licht, Petra Muus et al. · New England Journal of Medicine · 2013 · 1.6K citations · Full text

Medicine, Hematology, Pharmacotherapy +17

A Controlled Trial of High-Dose Intravenous Immune Globulin Infusions as Treatment for Dermatomyositis

Marinos C. Dalakas, Isabel Illa, James M. Dambrosia et al. · New England Journal of Medicine · 1993 · 1.1K citations · Full text

Medicine, Dermatology, Pharmacotherapy +17

Relative Role of Genetic Complement Abnormalities in Sporadic and Familial aHUS and Their Impact on Clinical Phenotype

Marina Noris, Jessica Caprioli, Elena Bresin et al. · Clinical Journal of the American Society of Nephrology · 2010 · 1K citations · Full text

Life Sciences, Genetics, Human Genetics +13

Executive summary of the KDIGO 2021 Guideline for the Management of Glomerular Diseases

Brad H. Rovin, Sharon G. Adler, Jonathan Barratt et al. · Kidney International · 2021 · 791 citations · Full text

Medicine, Internal Medicine, Nephrology +17

Genetics and Outcome of Atypical Hemolytic Uremic Syndrome

Véronique Frémeaux‐Bacchi, Fádi Fakhouri, Arnaud Garnier et al. · Clinical Journal of the American Society of Nephrology · 2013 · 713 citations

Life Sciences, Genetics, Nephrology +16

1–5 of 523

Authors

2.9K

VF
Véronique Frémeaux‐Bacchi
Hôpital Européen Georges-Pompidou, France
17 publications · 2.4K citations
15
h-index
MC
Matthew C. Pickering
Imperial College London, United Kingdom
10 publications · 1.5K citations
10
h-index
RJ
Richard J. Smith
University of Iowa, United States
10 publications · 1.4K citations
10
h-index
SR
Santiago Rodrı́guez de Córdoba
Centro de Investigaciones Biológicas Margarita Salas, Spain
8 publications · 1.4K citations
8
h-index
CN
Carla Nester
University of Iowa, United States
8 publications · 1.7K citations
8
h-index

1–5 of 2.9K

Institutions

923

1–8 of 923

Venues

PubMed
Repository · 54 publications · 2.1K citations
22
h-index
Blood
14 publications · 1.5K citations
13
h-index
Arthritis & Rheumatism
14 publications · 588 citations
13
h-index
Frontiers in Immunology
11 publications · 265 citations
11
h-index
The Journal of Immunology
JI · 11 publications · 774 citations
11
h-index

1–5