Concepedia

Complement Component Deficiency

Complement Component Deficiency is a genetic or acquired disorder characterized by the absence or dysfunction of a specific protein within the complement system, leading to impaired immune defense, inflammation regulation, or clearance of immune complexes.

828

Publications

48.4K

Citations

3.8K

Authors

1.1K

Institutions

Publications per year

2017–2026

81

Variants

Complement Deficiency

Parents

Publications

828

Schizophrenia risk from complex variation of complement component 4

Aswin Sekar, Heather de Rivera, Avery Davis et al. · Nature · 2016 · 2.5K citations · Full text

, , +16

C1q binds directly and specifically to surface blebs of apoptotic human keratinocytes: complement deficiency and systemic lupus erythematosus revisited

Laura C Korb, J M Ahearn · The Journal of Immunology · 1997 · 659 citations · Full text

, , +17

Hereditary and acquired angioedema: Problems and progress: Proceedings of the third C1 esterase inhibitor deficiency workshop and beyond

A Agostoni, Emel Aygören‐Pürsün, Karen Binkley et al. · Journal of Allergy and Clinical Immunology · 2004 · 643 citations · Full text

, , +10

Complement deficiency states and infection: epidemiology, pathogenesis and consequences of neisserial and other infections in an immune deficiency.

Stephen C. Ross, Peter Densen · PubMed · 1984 · 633 citations

, , +17

Complement C3 deficiency protects against neurodegeneration in aged plaque-rich APP/PS1 mice

Qiaoqiao Shi, Saba Chowdhury, Rong Ma et al. · Science Translational Medicine · 2017 · 595 citations · Full text

, , +17

1–5 of 828

Authors

3.8K

  1. RA
    Rick A. Wetsel

    Brown Foundation, United States

    16 publications · 1.2K citations

    15

    h-index

  2. FS
    Fred S. Rosen

    Harvard University, United States

    14 publications · 1.5K citations

    14

    h-index

  3. HR
    Harvey R. Colten

    Harvard University, United States

    15 publications · 1.1K citations

    13

    h-index

  4. LT
    Lennart Truedsson

    Lund University, Sweden

    16 publications · 526 citations

    13

    h-index

  5. BP
    B. Paul Morgan

    Cardiff University, United Kingdom

    13 publications · 467 citations

    13

    h-index

1–5 of 3.8K

Institutions

1.1K

  1. Harvard University

    Cambridge, United States

    33 h-index

    190 publications

    49.7K citations

  2. Washington University in St. Louis

    St Louis, United States

    20 h-index

    100 publications

    6.5K citations

  3. Boston Children's Hospital

    Boston, United States

    20 h-index

    86 publications

    22.8K citations

  4. Brigham and Women's Hospital

    Boston, United States

    20 h-index

    85 publications

    15.5K citations

  5. Lund University

    Lund, Sweden

    19 h-index

    82 publications

    2.8K citations

  6. Johannes Gutenberg University Mainz

    Mainz, Germany

    19 h-index

    78 publications

    4.8K citations

  7. Johns Hopkins University

    Baltimore, United States

    18 h-index

    67 publications

    6K citations

  8. University of Pennsylvania

    Philadelphia, United States

    14 h-index

    49 publications

    4K citations

1–8 of 1.1K

Venues

  1. The Journal of Immunology

    JI · 68 publications · 4.6K citations

    38

    h-index

  2. PubMed

    Repository · 111 publications · 4.6K citations

    37

    h-index

  3. Journal of Clinical Investigation

    JCI · 34 publications · 3.2K citations

    32

    h-index

  4. Infection and Immunity

    IAI · 25 publications · 1.5K citations

    21

    h-index

  5. Clinical & Experimental Immunology

    CEI · 25 publications · 868 citations

    19

    h-index

1–5