Darlene Groth

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Publications

Citations

16.6K

H-Index

Active since

1980

Affiliations

University of California, San Francisco(Current)

Institute for Neurodegenerative Disorders

McLaughlin Research Institute

Heinrich Heine University Düsseldorf

German Center for Neurodegenerative Diseases

Darlene Groth is an author at University of California, San Francisco specializing in prion protein misfolding, prion diseases, and molecular biology.

Publications per year

1980–2010

Publications

Conversion of alpha-helices into beta-sheets features in the formation of the scrapie prion proteins.

K M Pan, M. A. Baldwin, Jack Nguyen et al. · Proceedings of the National Academy of Sciences · 1993 · 2.3K citations

Life Sciences, Biochemistry, Molecular Biology +17

Eight prion strains have PrPSc molecules with different conformations

Jiri Safar, Holger Wille, Vincenza Itri et al. · Nature Medicine · 1998 · 1.2K citations

Life Sciences, Biochemistry, Molecular Biology +14

Scrapie prions aggregate to form amyloid-like birefringent rods

Stanley B. Prusiner, Michael P. McKinley, Karen A. Bowman et al. · Cell · 1983 · 1K citations

Life Sciences, Infectious Diseases, Molecular Biology +14

Transgenetic studies implicate interactions between homologous PrP isoforms in scrapie prion replication

Stanley B. Prusiner, Michael Scott, Dallas Foster et al. · Cell · 1990 · 869 citations

Life Sciences, Genetics, Molecular Biology +15

Scrapie and cellular PrP isoforms are encoded by the same chromosomal gene

Konrad Basler, Bruno Oesch, Michael Scott et al. · Cell · 1986 · 831 citations · Full text

Veterinary Medicine, Molecular Biology, Molecular Genetics +11

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