Jack Nguyen

Conversion of alpha-helices into beta-sheets features in the formation of the scrapie prion proteins.

K M Pan, M. A. Baldwin, Jack Nguyen et al. · Proceedings of the National Academy of Sciences · 1993 · 2.3K citations · Full text

Prpsc Synthesis, Protein Chemistry, Protein Secretion +15

pH-dependent structural transitions of Alzheimer amyloid peptides

Paul E. Fraser, Jack Nguyen, Witold K. Surewicz et al. · Biophysical Journal · 1991 · 377 citations · Full text

Alzheimer's Disease, Biochemistry, Protein Folding +3

Exploiting the Basis of Proline Recognition by SH3 and WW Domains: Design of N-Substituted Inhibitors

Jack Nguyen, Christoph W. Turck, Fred E. Cohen et al. · Science · 1998 · 316 citations

Drug Target, Critical Prolines, Signal Recognition +23

Fibril formation by primate, rodent, and Dutch-hemorrhagic analogs of Alzheimer amyloid .beta.-protein

Paul E. Fraser, Jack Nguyen, Hideyo Inouye et al. · Biochemistry · 1992 · 249 citations

Discovery of an allosteric site in the caspases

Jeanne A. Hardy, Joni W. Lam, Jack Nguyen et al. · Proceedings of the National Academy of Sciences · 2004 · 241 citations · Full text

Protein Assembly, Molecular Biology, Chemical Biology +17