Fred E. Cohen

Conversion of alpha-helices into beta-sheets features in the formation of the scrapie prion proteins.

K M Pan, M. A. Baldwin, Jack Nguyen et al. · Proceedings of the National Academy of Sciences · 1993 · 2.3K citations · Full text

Prpsc Synthesis, Protein Chemistry, Protein Secretion +15

Eight prion strains have PrPSc molecules with different conformations

Jiri Safar, Holger Wille, Vincenza Itri et al. · Nature Medicine · 1998 · 1.2K citations

Prion Strains, Structural Biology, Molecular Biology +1

An Evolutionary Trace Method Defines Binding Surfaces Common to Protein Families

Olivier Lichtarge, Henry R. Bourne, Fred E. Cohen · Journal of Molecular Biology · 1996 · 1.2K citations

Protein Families, Protein Assembly, Protein Folding +13

Synthetic Mammalian Prions

Giuseppe Legname, Ilia V. Baskakov, Hoang-Oanh B. Nguyen et al. · Science · 2004 · 1K citations

Prion propagation in mice expressing human and chimeric PrP transgenes implicates the interaction of cellular PrP with another protein

Glenn C. Telling, Michael Scott, James A. Mastrianni et al. · Cell · 1995 · 848 citations · Full text

Systems Biology, Protein Expression, Cellular Prp +5