Concepedia

Complement System Dysfunction

Complement System Dysfunction is a pathological condition characterized by aberrant activity or regulation of the complement system, a component of the innate immune response, leading to either excessive or insufficient immune activation that contributes to tissue damage, autoimmune disorders, or increased susceptibility to infections.

1.1K

Publications

63.1K

Citations

5.9K

Authors

1.4K

Institutions

Publications per year

2017–2026

253

Parents

Publications

1.1K

Complement and microglia mediate early synapse loss in Alzheimer mouse models

Soyon Hong, Victoria F. Beja-Glasser, Bianca M. Nfonoyim et al. · Science · 2016 · 3.4K citations · Full text

, , +17

Relative Role of Genetic Complement Abnormalities in Sporadic and Familial aHUS and Their Impact on Clinical Phenotype

Marina Noris, Jessica Caprioli, Elena Bresin et al. · Clinical Journal of the American Society of Nephrology · 2010 · 1K citations · Full text

, , +13

Activation of the Complement System During and After Cardiopulmonary Bypass Surgery

Peter Bruins, Henk te Velthuis, Aria P. Yazdanbakhsh et al. · Circulation · 1997 · 804 citations

, , +15

Complement Activation Contributes to Severe Acute Respiratory Syndrome Coronavirus Pathogenesis

Lisa E. Gralinski, Timothy P. Sheahan, Thomas E. Morrison et al. · mBio · 2018 · 700 citations · Full text

, , +17

Recent advances on the complement system of teleost fish

Hani Boshra, Jun Li, J. Oriol Sunyer · Fish & Shellfish Immunology · 2005 · 674 citations

, , +13

1–5 of 1.1K

Authors

5.9K

  1. VF
    Véronique Frémeaux‐Bacchi

    Hôpital Européen Georges-Pompidou, France

    15 publications · 935 citations

    15

    h-index

  2. ST
    Steffen Thiel

    Aarhus University, Denmark

    17 publications · 971 citations

    14

    h-index

  3. BP
    B. Paul Morgan

    Cardiff University, United Kingdom

    13 publications · 514 citations

    13

    h-index

  4. TE
    Tom Eirik Mollnes

    Oslo University Hospital, Norway

    13 publications · 915 citations

    12

    h-index

  5. HG
    H Gewurz

    Rush University Medical Center, United States

    12 publications · 667 citations

    12

    h-index

1–5 of 5.9K

Institutions

1.4K

  1. Harvard University

    Cambridge, United States

    23 h-index

    131 publications

    33K citations

  2. Lund University

    Lund, Sweden

    20 h-index

    85 publications

    6.9K citations

  3. Washington University in St. Louis

    St Louis, United States

    19 h-index

    70 publications

    2.8K citations

  4. University of Minnesota

    Minneapolis, United States

    18 h-index

    64 publications

    7.6K citations

  5. Aarhus University

    Aarhus, Denmark

    17 h-index

    54 publications

    3.2K citations

  6. University of Pennsylvania

    Philadelphia, United States

    17 h-index

    51 publications

    5.1K citations

  7. University of Colorado Denver

    Denver, United States

    16 h-index

    61 publications

    3.8K citations

  8. Heidelberg University

    Heidelberg, Germany

    16 h-index

    60 publications

    2.6K citations

1–8 of 1.4K

Venues

  1. PubMed

    Repository · 144 publications · 5.5K citations

    40

    h-index

  2. Journal of Clinical Investigation

    JCI · 28 publications · 2.8K citations

    27

    h-index

  3. The Journal of Immunology

    JI · 33 publications · 2.1K citations

    23

    h-index

  4. PLoS ONE

    30 publications · 1.5K citations

    22

    h-index

  5. Frontiers in Immunology

    33 publications · 1K citations

    20

    h-index

1–5