Concepedia

Metabolic Activation

Metabolic Activation is the metabolic conversion of a xenobiotic compound into a chemically reactive intermediate through enzymatic transformation, distinguishing it from direct-acting toxins by requiring bioactivation to exert toxic effects.

2.4K

Publications

123.8K

Citations

8.7K

Authors

1.8K

Institutions

Publications per year

2017–2026

398

Variants

Bioactivation

Parents

Children

Publications

2.4K

Transcriptional Adaptation of <i>Mycobacterium tuberculosis</i> within Macrophages

Dirk Schnappinger, Sabine Ehrt, Martin I. Voskuil et al. · The Journal of Experimental Medicine · 2003 · 1.4K citations · Full text

, , +17

Metabolism and Physiology of Abscisic Acid

J. A. D. Zeevaart, Robert A. Creelman · Annual Review of Plant Physiology and Plant Molecular Biology · 1988 · 1.4K citations

, , +12

Occurrence, metabolism, metabolic role, and industrial uses of bacterial polyhydroxyalkanoates.

Alistair J. Anderson, E. A. Dawes · Microbiological Reviews · 1990 · 1.3K citations · Full text

, , +16

Metabolic activation of benzo(a)pyrene proceeds by a diol-epoxide

Peter Sims, P.L. Grover, Alan Swaisland et al. · Nature · 1974 · 1.1K citations

, , +12

Antibiotic efficacy is linked to bacterial cellular respiration

Michael A. Lobritz, Peter Belenky, Caroline Porter et al. · Proceedings of the National Academy of Sciences · 2015 · 786 citations · Full text

, , +17

1–5 of 2.4K

Authors

8.7K

  1. HG
    Hansruedi Glatt

    German Institute of Human Nutrition, Germany

    28 publications · 1.2K citations

    21

    h-index

  2. FP
    F. Peter Guengerich

    Vanderbilt University, United States

    22 publications · 2.1K citations

    17

    h-index

  3. FJ
    Frank J. Gonzalez

    National Cancer Institute, United States

    17 publications · 1.6K citations

    16

    h-index

  4. FO
    Franz Oesch

    Johannes Gutenberg University Mainz, Germany

    19 publications · 823 citations

    15

    h-index

  5. TP
    T.M. Penning

    University of Pennsylvania, United States

    14 publications · 1K citations

    14

    h-index

1–5 of 8.7K

Institutions

1.8K

  1. National Institutes of Health

    Bethesda, United States

    36 h-index

    136 publications

    12.1K citations

  2. National Cancer Institute

    Bethesda, United States

    26 h-index

    67 publications

    6K citations

  3. Centre National de la Recherche Scientifique

    Paris, France

    24 h-index

    153 publications

    5.2K citations

  4. Chinese Academy of Sciences

    Beijing, China

    21 h-index

    129 publications

    6.4K citations

  5. University of Illinois Urbana-Champaign

    Urbana, United States

    20 h-index

    64 publications

    3.2K citations

  6. Vanderbilt University

    Nashville, United States

    20 h-index

    75 publications

    5.7K citations

  7. Johannes Gutenberg University Mainz

    Mainz, Germany

    19 h-index

    101 publications

    4.3K citations

  8. University of Michigan

    Ann Arbor, United States

    19 h-index

    70 publications

    5.1K citations

1–8 of 1.8K

Venues

  1. PubMed

    Repository · 134 publications · 6.7K citations

    47

    h-index

  2. Journal of Bacteriology

    JB · 82 publications · 5.1K citations

    44

    h-index

  3. Journal of Biological Chemistry

    JBC · 75 publications · 7.6K citations

    43

    h-index

  4. Biochemistry

    89 publications · 4.7K citations

    39

    h-index

  5. Journal of the American Chemical Society

    JACS · 53 publications · 3.1K citations

    36

    h-index

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