F. Peter Guengerich

Interindividual variations in human liver cytochrome P-450 enzymes involved in the oxidation of drugs, carcinogens and toxic chemicals: studies with liver microsomes of 30 Japanese and 30 Caucasians.

Tsutomu Shimada, Hiroshi Yamazaki, Mayumi Mimura et al. · Journal of Pharmacology and Experimental Therapeutics · 1994 · 2.8K citations

Medicine, Biochemistry, Pharmacology +15

Purification and characterization of liver microsomal cytochromes P-450: electrophoretic, spectral, catalytic, and immunochemical properties and inducibility of eight isozymes isolated from rats treated with phenobarbital or .beta.-naphthoflavone

F. Peter Guengerich, Ghazi A. Dannan, Stephen Wright et al. · Biochemistry · 1982 · 1K citations

Medicine, Biochemistry, Pharmacology +12

Mapping the Genetic Architecture of Gene Expression in Human Liver

Eric E. Schadt, Cliona Molony, Eugene Chudin et al. · PLoS Biology · 2008 · 928 citations · Full text

Life Sciences, Genetics, Molecular Genetics +17

The P450 Gene Superfamily: Recommended Nomenclature

Daniel W. Nebert, Milton Adesnik, Minor J. Coon et al. · DNA · 1987 · 815 citations

Life Sciences, Genetics, Molecular Genetics +15

Characterization of rat and human liver microsomal cytochrome P-450 forms involved in nifedipine oxidation, a prototype for genetic polymorphism in oxidative drug metabolism.

F. Peter Guengerich, M V Martin, Philippe Beaune et al. · Journal of Biological Chemistry · 1986 · 730 citations · Full text

Medicine, Biochemistry, Pharmacology +17