Concepedia

Tsutomu Shimada

TS

Statistics

Publications

225

Citations

19.5K

H-Index

71

Active since

1970

Affiliations

Osaka Prefectural Institute of Public Health(Current)

Vanderbilt University

Musashino University

Kanazawa University

Showa Pharmaceutical University

Tsutomu Shimada is an author at Osaka Prefectural Institute of Public Health specializing in medicine, biochemistry, and pharmacology.

ORCID

Top concepts

Publications per year

1970–2020

225

Publications

225

Interindividual variations in human liver cytochrome P-450 enzymes involved in the oxidation of drugs, carcinogens and toxic chemicals: studies with liver microsomes of 30 Japanese and 30 Caucasians.

Tsutomu Shimada, Hiroshi Yamazaki, Mayumi Mimura et al. · Journal of Pharmacology and Experimental Therapeutics · 1994 · 2.8K citations

Activation of chemically diverse procarcinogens by human cytochrome P-450 1B1.

Tsutomu Shimada, Carrie L. Hayes, Hiroshi Yamazaki et al. · PubMed · 1996 · 795 citations

, , +17

Cytochrome P450 2E1 and 2A6 enzymes as major catalysts for metabolic activation of <i>N</i>-nitrosodialkylamines and tobacco-related nitrosamines in human liver microsomes

Hiroshi Yamazaki, Yukiharu Inui, Chul‐Ho Yun et al. · Carcinogenesis · 1992 · 394 citations

Progesterone and Testosterone Hydroxylation by Cytochromes P450 2C19, 2C9, and 3A4 in Human Liver Microsomes

Hiroshi Yamazaki, Tsutomu Shimada · Archives of Biochemistry and Biophysics · 1997 · 309 citations

, , +11

Evidence for cytochrome P-450NF, the nifedipine oxidase, being the principal enzyme involved in the bioactivation of aflatoxins in human liver.

Tsutomu Shimada, F. Peter Guengerich · Proceedings of the National Academy of Sciences · 1989 · 303 citations · Full text

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1–5 of 225