Cell-cell Communication

Cell-cell communication is an intercellular signaling process in which cells transmit and receive information via extracellular molecules or direct contact, enabling the coordination of their physiological activities and responses.

3.2K

Publications

286.1K

Citations

12.9K

Authors

2.4K

Institutions

Publications per year

2017–2026

622

Parents

Cell Biology

Children

Autocrine SignalingCalcium SignalingCell Polarity SignalingChemokine SignalingContact-dependent SignalingCytokine SignalingDevelopmental Cell SignalingEndocrine SignalingEpithelial Cell CommunicationExtracellular Vesicle Signaling

Publications

3.2K

Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells

Hadi Valadi, Karin M. Ekström, Apostolos Bossios et al. · Nature Cell Biology · 2007 · 12.8K citations

Life Sciences, Genetics, Molecular Biology +12

Inference and analysis of cell-cell communication using CellChat

Suoqin Jin, Christian F. Guerrero‐Juarez, Lihua Zhang et al. · Nature Communications · 2021 · 8.3K citations · Full text

Life Sciences, Bioinformatics, Cell Biology +17

CellPhoneDB: inferring cell–cell communication from combined expression of multi-subunit ligand–receptor complexes

Mirjana Efremova, Miquel Vento-Tormo, Sarah A. Teichmann et al. · Nature Protocols · 2020 · 3.6K citations

Life Sciences, Bioinformatics, Molecular Biology +16

Principles of animal communication

Choice Reviews Online · 2012 · 2.6K citations

Life Sciences, Animal Sciences, Communication +12

NicheNet: modeling intercellular communication by linking ligands to target genes

Robin Browaeys, Wouter Saelens, Yvan Saeys · Nature Methods · 2019 · 2.2K citations

Life Sciences, Cell Biology, Molecular Biology +12

1–5 of 3.2K

Authors

12.9K

JE
James E. Trosko
Michigan State University, United States
27 publications · 1.3K citations
20
h-index
HY
Hiroshi Yamasaki
Centre international de recherche sur le cancer, France
19 publications · 1.3K citations
17
h-index
WR
W. R. Loewenstein
University of Miami, United States
15 publications · 1.8K citations
15
h-index
DC
David C. Spray
Albert Einstein College of Medicine, United States
16 publications · 1.3K citations
14
h-index
KW
Klaus Willecke
University of Bonn, Germany
16 publications · 1.5K citations
14
h-index

1–5 of 12.9K

Institutions

2.4K

1–8 of 2.4K

Venues

Nature
85 publications · 20.9K citations
53
h-index
Proceedings of the National Academy of Sciences
PNAS · 72 publications · 9.8K citations
52
h-index
PubMed
Repository · 136 publications · 6.2K citations
46
h-index
The Journal of Cell Biology
JCB · 47 publications · 8.2K citations
43
h-index
Journal of Biological Chemistry
JBC · 48 publications · 6.9K citations
40
h-index

1–5

See also Cell-cell Communication
Signaling Mechanisms	Paracrine Signaling Juxtacrine Signaling Autocrine Signaling Endocrine Signaling Synaptic Signaling Gap Junction Communication Ligand-receptor Interactions
Molecular Mediators	Gap Junctions Ligand Binding Receptors Cell-surface Receptors Intracellular Receptors Growth Factors Cytokine Biology Adhesion Molecules Extracellular Vesicles
Biological Functions	Morphogenesis Cell Fate Determination Cell Differentiation Tissue Homeostasis Wound Healing Cell Proliferation Immune Response Immune Homeostasis Fetal Organ Development Tissue Regeneration Stem Cell Niche
Experimental Methods	Single-cell Rna Sequencing Spatial Transcriptomics In Situ Hybridization Immunohistochemistry Immunofluorescence Imaging Rna Interference Gene Knockout Transmission Electron Microscopy Microfluidic Cell Culture Sequence-specific Gene Knockdown Yeast Two-hybrid Screening Co-immunoprecipitation Analysis Proximity Labeling Proteomics Fluorescence Resonance Energy Transfer X-ray Crystallography Bulk Rna Sequencing Single-cell Proteomics Single-cell Epigenomics
Pathological Dysregulation	Tumor Microenvironment Relay Networks Fibrotic Interstitial Lung Disease Multisystem Inflammatory Syndrome Synaptic Transmission Immune Evasion