Concepedia

Stem Cell Niche

Stem Cell Niche is a specialized anatomical and functional microenvironment within a tissue that houses stem cells and regulates their maintenance, self-renewal, proliferation, and differentiation through defined molecular cues, cell–cell and cell–matrix interactions, and biophysical factors.

1.7K

Publications

219.6K

Citations

9.7K

Authors

2K

Institutions

Publications per year

2017–2026

574

Variants

Stem Cell ActivationStem Cell AgingStem Cell AsymmetryStem Cell EpigeneticsStem Cell MicroenvironmentStem Cell NichesStem Cell PlasticityStem Cell PotencyStem Cell PropertiesStem Cell Quiescence

Parents

Children

Publications

1.7K

Single Lgr5 stem cells build crypt-villus structures in vitro without a mesenchymal niche

Toshiro Sato, Robert G.J. Vries, Hugo J.G. Snippert et al. · Nature · 2009 · 7.2K citations

, , +14

Identification of stem cells in small intestine and colon by marker gene Lgr5

Nick Barker, Johan H. van Es, Jeroen Kuipers et al. · Nature · 2007 · 5.7K citations

, , +16

Osteoblastic cells regulate the haematopoietic stem cell niche

Laura M. Calvi, G. B. Adams, Kathryn Weibrecht et al. · Nature · 2003 · 3.4K citations

, , +13

Mesenchymal and haematopoietic stem cells form a unique bone marrow niche

Simón Méndez‐Ferrer, Tatyana V. Michurina, Francesca Ferraro et al. · Nature · 2010 · 3.3K citations

, , +14

SLAM Family Receptors Distinguish Hematopoietic Stem and Progenitor Cells and Reveal Endothelial Niches for Stem Cells

Mark J. Kiel, Ömer Yılmaz, Toshihide Iwashita et al. · Cell · 2005 · 3.1K citations · Full text

, , +15

1–5 of 1.7K

Authors

9.7K

  1. HC
    Hans Clevers

    Hubrecht Institute for Developmental Biology and Stem Cell Research, Netherlands

    19 publications · 20.1K citations

    19

    h-index

  2. DT
    David T. Scadden

    Massachusetts General Hospital, United States

    20 publications · 11.9K citations

    19

    h-index

  3. EF
    Elaine Fuchs

    Howard Hughes Medical Institute, United States

    17 publications · 6.4K citations

    17

    h-index

  4. CL
    Cristina Lo Celso

    Imperial College London, United Kingdom

    15 publications · 3.1K citations

    15

    h-index

  5. PS
    Paul S. Frenette

    Albert Einstein College of Medicine, United States

    13 publications · 6.7K citations

    13

    h-index

1–5 of 9.7K

Institutions

2K

  1. Harvard University

    Cambridge, United States

    48 h-index

    268 publications

    100.5K citations

  2. Howard Hughes Medical Institute

    Chevy Chase, United States

    48 h-index

    185 publications

    67.8K citations

  3. Stanford University

    Stanford, United States

    40 h-index

    275 publications

    51.8K citations

  4. University of Cambridge

    Cambridge, United Kingdom

    34 h-index

    153 publications

    17.9K citations

  5. Inserm

    Paris, France

    33 h-index

    226 publications

    24.4K citations

  6. University of Michigan

    Ann Arbor, United States

    33 h-index

    204 publications

    49.6K citations

  7. Centre National de la Recherche Scientifique

    Paris, France

    32 h-index

    198 publications

    15.2K citations

  8. Heidelberg University

    Heidelberg, Germany

    31 h-index

    193 publications

    29.4K citations

1–8 of 2K

Venues

  1. Nature

    58 publications · 42.7K citations

    52

    h-index

  2. Cell stem cell

    56 publications · 14.2K citations

    50

    h-index

  3. Proceedings of the National Academy of Sciences

    PNAS · 53 publications · 9.9K citations

    44

    h-index

  4. Stem Cells

    58 publications · 6.3K citations

    38

    h-index

  5. Blood

    48 publications · 7.5K citations

    38

    h-index

1–5