Concepedia

Author

Nick Barker

Hubrecht Institute for Developmental Biology and Stem Cell ResearchORCID

Also Known As

Barker, Nicholas, Gaetano Gargiulo, N Barker, N. Barker, Nicholas Barker, Nick BARKER, Nick Barker

206

Publications

52K

Citations

72

H-Index

103

Concepts

All Affiliations

Hubrecht Institute for Developmental Biology and Stem Cell ResearchInstitute of Medical BiologyAgency for Science, Technology and ResearchUniversity Medical Center UtrechtNational University of Singapore
NB

About

Nick Barker is an author at Hubrecht Institute for Developmental Biology and Stem Cell Research specializing in medicine, cell biology, and developmental biology.

Top Concepts

#ConceptH-IndexPublicationsCitations

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Medicine

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38.2K

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Health Sciences

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Business

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Engineering

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Management

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Nick Barker

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81

Publications

44.5K

Citations

59

H-Index

YearCitations

Single Lgr5 stem cells build crypt-villus structures in vitro without a mesenchymal niche

Toshiro Sato, Robert G.J. Vries, Hugo J.G. Snippert,

Nature

2009

6.9K

Identification of stem cells in small intestine and colon by marker gene Lgr5

Nick Barker, Johan H. van Es, Jeroen Kuipers,

Nature

2007

5.6K

Activation of β-Catenin-Tcf Signaling in Colon Cancer by Mutations in β-Catenin or APC

Patrice J. Morin, Andrew B. Sparks, Vladimír Kořínek,

Science

1997

3.9K

Constitutive Transcriptional Activation by a β-Catenin-Tcf Complex in APC <sup>−/−</sup> Colon Carcinoma

Vladimír Kořínek, Nick Barker, Patrice J. Morin,

Science

1997

3.3K

Paneth cells constitute the niche for Lgr5 stem cells in intestinal crypts

Toshiro Sato, Johan H. van Es, Hugo J.G. Snippert,

Nature

2010

2.4K

Crypt stem cells as the cells-of-origin of intestinal cancer

Nick Barker, Rachel A. Ridgway, Johan H. van Es,

Nature

2008

2.1K

Intestinal Crypt Homeostasis Results from Neutral Competition between Symmetrically Dividing Lgr5 Stem Cells

Hugo J.G. Snippert, Laurens G. van der Flier, Toshiro Sato,

Cell

2010

1.9K

Depletion of epithelial stem-cell compartments in the small intestine of mice lacking Tcf-4

Vladimír Kořínek, Nick Barker, Petra Moerer,

Nature Genetics

1998

1.6K

Lgr5+ve Stem Cells Drive Self-Renewal in the Stomach and Build Long-Lived Gastric Units In Vitro

Nick Barker, Meritxell Huch, Pekka Kujala,

Cell stem cell

2010

1.5K

Lgr5 homologues associate with Wnt receptors and mediate R-spondin signalling

Wim de Lau, Nick Barker, Teck Yew Low,

Nature

2011

1.3K

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