Hugo J.G. Snippert

Single Lgr5 stem cells build crypt-villus structures in vitro without a mesenchymal niche

Toshiro Sato, Robert G.J. Vries, Hugo J.G. Snippert et al. · Nature · 2009 · 7.2K citations

Life Sciences, Cell Biology, Developmental Biology +14

Paneth cells constitute the niche for Lgr5 stem cells in intestinal crypts

Toshiro Sato, Johan H. van Es, Hugo J.G. Snippert et al. · Nature · 2010 · 2.5K citations

Life Sciences, Cell Biology, Developmental Biology +15

Intestinal Crypt Homeostasis Results from Neutral Competition between Symmetrically Dividing Lgr5 Stem Cells

Hugo J.G. Snippert, Laurens G. van der Flier, Toshiro Sato et al. · Cell · 2010 · 2K citations · Full text

Life Sciences, Biology, Cell Biology +16

Lgr5+ve Stem Cells Drive Self-Renewal in the Stomach and Build Long-Lived Gastric Units In Vitro

Nick Barker, Meritxell Huch, Pekka Kujala et al. · Cell stem cell · 2010 · 1.5K citations · Full text

Life Sciences, Cell Biology, Developmental Biology +10

Sequential cancer mutations in cultured human intestinal stem cells

Jarno Drost, Richard H. van Jaarsveld, Bas Ponsioen et al. · Nature · 2015 · 1.1K citations · Full text

Life Sciences, Cell Biology, Oncology +14