Concepedia

Intestinal Crypt Homeostasis Results from Neutral Competition between Symmetrically Dividing Lgr5 Stem Cells

Hugo J.G. Snippert, Laurens G. van der Flier, Toshiro Sato, Johan H. van Es, Maaike van den Born, Carla Kroon-Veenboer, Nick Barker, Allon M. Klein, Jacco van Rheenen, Benjamin D. Simons,

Cell · 2010 · 2K citations · 33 references

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Concepts

References

33

The Neutral Theory of Molecular Evolution

Scientific American · 1979 · 7.8K citations

, , +14

Single Lgr5 stem cells build crypt-villus structures in vitro without a mesenchymal niche

Toshiro Sato, Robert G.J. Vries, Hugo J.G. Snippert et al. · Nature · 2009 · 7.2K citations

, , +14

Identification of stem cells in small intestine and colon by marker gene Lgr5

Nick Barker, Johan H. van Es, Jeroen Kuipers et al. · Nature · 2007 · 5.7K citations

, , +16

The Potts model

F. Y. Wu · Reviews of Modern Physics · 1982 · 3.6K citations

, , +14

Transgenic strategies for combinatorial expression of fluorescent proteins in the nervous system

Jean Livet, Tamily A. Weissman, Hyuno Kang et al. · Nature · 2007 · 1.9K citations

, , +17