Concepedia

Crypt Architecture

Crypt Architecture is a histological structure in the gastrointestinal epithelium characterized by its invaginated glandular units, or crypts of Lieberkühn, which house intestinal stem cells and support epithelial regeneration, secretion, and barrier maintenance through spatially organized cellular differentiation and proliferation.

733

Publications

52K

Citations

3.2K

Authors

903

Institutions

Publications per year

2017–2026

124

Variants

Cryptal Architecture

Parents

Publications

733

Paneth cells constitute the niche for Lgr5 stem cells in intestinal crypts

Toshiro Sato, Johan H. van Es, Hugo J.G. Snippert et al. · Nature · 2010 · 2.5K citations

, , +15

Intestinal Crypt Homeostasis Results from Neutral Competition between Symmetrically Dividing Lgr5 Stem Cells

Hugo J.G. Snippert, Laurens G. van der Flier, Toshiro Sato et al. · Cell · 2010 · 2K citations · Full text

, , +16

Clinicopathologic study of dextran sulfate sodium experimental acute colitis

Kazuko Shichijo, Mutsumi Matuu, Yuji Ikeda et al. · The Japanese Journal of Pharmacology · 1998 · 2K citations · Full text

, , +17

Observation and quantification of aberrant crypts in the murine colon treated with a colon carcinogen: Preliminary findings

Ranjana P. Bird · Cancer Letters · 1987 · 1K citations

, , +15

Topological control of p21WAF1/CIP1 expression in normal and neoplastic tissues.

Wafik S. El‐Deiry, Takashi Tokino, Todd Waldman et al. · PubMed · 1995 · 590 citations

, , +16

1–5 of 733

Authors

3.2K

  1. NA
    Nicholas A. Wright

    Hammersmith Hospital, United Kingdom

    14 publications · 1.2K citations

    13

    h-index

  2. HC
    Hazel Cheng

    University of Toronto, Canada

    12 publications · 1.8K citations

    12

    h-index

  3. MB
    Matthew Bjerknes

    University of Toronto, Canada

    10 publications · 856 citations

    10

    h-index

  4. CS
    Christopher S. Potten

    Cancer Research UK Manchester Institute, United Kingdom

    9 publications · 871 citations

    9

    h-index

  5. ML
    Markus Loeffler

    Leipzig University, Germany

    7 publications · 632 citations

    7

    h-index

1–5 of 3.2K

Institutions

903

  1. University of Toronto

    Toronto, Canada

    13 h-index

    39 publications

    3.4K citations

  2. University of North Carolina at Chapel Hill

    Chapel Hill, United States

    12 h-index

    51 publications

    5.3K citations

  3. Cancer Research UK Manchester Institute

    Manchester, United Kingdom

    11 h-index

    29 publications

    2.8K citations

  4. Hebrew University of Jerusalem

    Jerusalem, Israel

    11 h-index

    29 publications

    4.3K citations

  5. Université de Sherbrooke

    Sherbrooke, Canada

    10 h-index

    51 publications

    2.3K citations

  6. North Carolina State University

    Raleigh, United States

    10 h-index

    31 publications

    2.5K citations

  7. Washington University in St. Louis

    St Louis, United States

    10 h-index

    37 publications

    4.6K citations

  8. University College London

    London, United Kingdom

    10 h-index

    53 publications

    5.8K citations

1–8 of 903

Venues

  1. PubMed

    Repository · 53 publications · 2.7K citations

    28

    h-index

  2. Gut

    25 publications · 2.3K citations

    23

    h-index

  3. 21

    h-index

  4. Cell Proliferation

    23 publications · 1.2K citations

    19

    h-index

  5. American Journal of Anatomy

    16 publications · 2.1K citations

    15

    h-index

1–5